Rhodium(I)-Catalyzed Pauson–Khand-type [3 + 2 + 1] Cycloaddition Reaction of Ene-Vinylidenecyclopropanes and CO: A Highly Regio- and Stereoselective Synthetic Approach for the Preparation of Aza- and Oxa-Bicyclic Compounds
| العنوان: | Rhodium(I)-Catalyzed Pauson–Khand-type [3 + 2 + 1] Cycloaddition Reaction of Ene-Vinylidenecyclopropanes and CO: A Highly Regio- and Stereoselective Synthetic Approach for the Preparation of Aza- and Oxa-Bicyclic Compounds |
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| المؤلفون: | Yin Wei, Bei-Li Lu, Min Shi |
| المصدر: | Organometallics. 31:4601-4609 |
| بيانات النشر: | American Chemical Society (ACS), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Bicyclic molecule, Chemistry, Organic Chemistry, Substrate (chemistry), chemistry.chemical_element, Cyclohexanone, Combinatorial chemistry, Cycloaddition, Catalysis, Rhodium, Inorganic Chemistry, chemistry.chemical_compound, Organic chemistry, Stereoselectivity, Physical and Theoretical Chemistry, Ene reaction |
| الوصف: | In this paper, a novel Rh(I)-catalyzed Pauson–Khand-type [3 + 2 + 1] cycloaddition reaction of ene-vinylidenecyclopropanes (Ene-VDCPs) and carbon monoxide (CO) has been developed to furnish a series of aza- and oxa-bicyclic compounds in moderate to good yields in a highly regio- and diastereoselective manner, which provides an alternative and efficient synthetic approach for the access of bicyclic cyclohexanone frameworks. The substrate scope and limitations and a plausible mechanism are discussed. |
| تدمد: | 1520-6041 0276-7333 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::08e64e39d75008ed3895bd30529e2450Test https://doi.org/10.1021/om3004288Test |
| رقم الانضمام: | edsair.doi...........08e64e39d75008ed3895bd30529e2450 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206041 02767333 |
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