Access to Polycyclic Indole-3,4-Fused Nine-Membered Ring via Cascade 1,6-Hydride Transfer/Cyclization
| العنوان: | Access to Polycyclic Indole-3,4-Fused Nine-Membered Ring via Cascade 1,6-Hydride Transfer/Cyclization |
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| المؤلفون: | Rui-Bin Liu, Shuo Yang, Bin Qiu, Jian Xiao, Xiao-De An |
| المصدر: | Organic Letters. 23:9100-9105 |
| بيانات النشر: | American Chemical Society (ACS), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Indole test, Aldimine, Hydride, Organic Chemistry, Condensation, Ring (chemistry), Biochemistry, Combinatorial chemistry, Aldehyde, chemistry, Cascade, Amine gas treating, Physical and Theoretical Chemistry |
| الوصف: | A cascade aldimine condensation/1,6-hydride transfer/Mannich-type cyclization of indole-derived phenylenediamine with aldehydes was developed for one-step construction of a polycyclic indole-3,4-fused skeleton. Aldehyde serves as a key to start the whole process, including 1,6-hydride transfer enabled δ-C(sp3)-H activation of the secondary amine. The challenges of construction of medium-sized rings are addressed via hydride transfer chemistry. |
| تدمد: | 1523-7052 1523-7060 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253558b8059b180118b1f3f574b854c8Test https://doi.org/10.1021/acs.orglett.1c03389Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....253558b8059b180118b1f3f574b854c8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15237052 15237060 |
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