Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis
| العنوان: | Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis |
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| المؤلفون: | Gui-Zhen Yang, Xiao-Wei Cong, Ya-Wen Wang, Yu Peng, Jian Xiao |
| المصدر: | Organic Letters. 20:1651-1654 |
| بيانات النشر: | American Chemical Society (ACS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | biology, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, Podophyllum, 010402 general chemistry, biology.organism_classification, 01 natural sciences, Biochemistry, 0104 chemical sciences, Catalysis, Podophyllotoxin, medicine, Stereoselectivity, Physical and Theoretical Chemistry, medicine.drug |
| الوصف: | A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent cores embedded in podophyllum lignans is developed for the first time. Their gram-scale access paved the way for unified syntheses of naturally occurring podophyllotoxin and other members. |
| تدمد: | 1523-7052 1523-7060 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed5e1e3f3d75acfafbc9f693850c6dbTest https://doi.org/10.1021/acs.orglett.8b00408Test |
| رقم الانضمام: | edsair.doi.dedup.....aed5e1e3f3d75acfafbc9f693850c6db |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15237052 15237060 |
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