التفاصيل البيبلوغرافية
| العنوان: |
Is Targeting the Folate Receptor in Ovarian Cancer Coming of Age? |
| المؤلفون: |
Birrer, Michael J., Betella, Ilaria, Martin, Lainie P., Moore, Kathleen N. |
| المصدر: |
Oncologist; Apr2019, Vol. 24 Issue 4, p425-429, 5p, 2 Diagrams, 2 Charts |
| مصطلحات موضوعية: |
ANTINEOPLASTIC agents, THERAPEUTIC use of immunoglobulins, THERAPEUTIC use of monoclonal antibodies, CANCER patient medical care, CELL receptors, DRUG delivery systems, DRUG resistance in cancer cells, ENDOCYTOSIS, EPITHELIAL cell tumors, FOLIC acid, GENE expression, MOLECULAR structure, OVARIAN tumors, SURVIVAL, DISEASE management, PROGNOSIS |
| مستخلص: |
Prognosis for women with epithelial ovarian cancer remains poor. One new molecular target in epithelial ovarian cancer is folate receptor alpha (FRα). This commentary discusses the characteristics that contribute to its attractiveness as a candidate for therapeutic intervention. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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