دورية أكاديمية
Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC)
| العنوان: | Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) |
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| المؤلفون: | Anderson, H. R., Ruggles, R., Pandey, K.D., Kapetanakis, V., Brunekreef, B., Lai, C. K. W., Strachan, D. P., Weiland, S. K., Aït-Khaled, N., Anabwani, G., Asher, M. I., Beasley, R., Björkstén, B., Burr, M. L., Crane, J., Keil, U., Mallol, J., Martinez, F. C., Mitchell, E. A., Montefort, S., Pearce, N., Robertson, C. F., Shah, J. R., Stewart, A. W., Mutius, Erika von, Williams, H. C., Clayton, T. O., Ellwood, P. |
| المصدر: | Occupational and Environmental Medicine |
| بيانات النشر: | Ludwig-Maximilians-Universität München |
| سنة النشر: | 2010 |
| المجموعة: | Open Access LMU (Ludwig-Maximilians-University Munich) |
| مصطلحات موضوعية: | Medizin, ddc:610 |
| الوصف: | Objectives: To investigate the effect of ambient particulate matter on variation in childhood prevalence of asthma, rhinoconjunctivitis and eczema. Methods: Prevalences of asthma, rhinoconjunctivitis and eczema obtained in Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) were matched with city-level estimates of residential PM10 obtained from a World Bank model. Associations were investigated using binomial regression adjusting for GNP per capita and for clustering within country. For countries with more than one centre, a two stage meta-analysis was carried out. The results were compared with a meta-analysis of published multi-centre studies. Results: Annual concentrations of PM₁₀ at city level were obtained for 105 ISAAC centres in 51 countries. After controlling for GNP per capita, there was a weak negative association between PM₁₀ and various outcomes. For severe wheeze in 13-14-year-olds, the OR for a 10 μg/m³ increase in PM₁₀ was 0.92 (95 CI 0.84 to 1.00). In 24 countries with more than one centre, most summary estimates for within-country associations were weakly positive. For severe wheeze in 13-14-year-olds, the summary OR for a 10 μg/m³ increase in PM₁₀ was 1.01 (0.92 to 1.10). This result was close to a summary OR of 0.99 (0.91 to 1.06) obtained from published multi-centre studies. Conclusions: Modelled estimates of particulate matter at city level are imprecise and incomplete estimates of personal exposure to ambient air pollutants. Nevertheless, our results together with those of previous multi-centre studies, suggest that urban background PM₁₀ has little or no association with the prevalence of childhood asthma, rhinoconjunctivitis or eczema either within or between countries. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Anderson, H. R.; Ruggles, R.; Pandey, K.D.; Kapetanakis, V.; Brunekreef, B.; Lai, C. K. W.; Strachan, D. P.; Weiland, S. K.; Aït-Khaled, N.; Anabwani, G.; Asher, M. I.; Beasley, R.; Björkstén, B.; Burr, M. L.; Crane, J.; Keil, U.; Mallol, J.; Martinez, F. C.; Mitchell, E. A.; Montefort, S.; Pearce, N.; Robertson, C. F.; Shah, J. R.; Stewart, A. W.; Mutius, Erika von; Williams, H. C.; Clayton, T. O.; Ellwood, P. (2010): Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC). In: Occupational and Environmental Medicine, Vol. 67, Nr. 5: S. 293-300 [PDF, 168kB]; https://epub.ub.uni-muenchen.de/18016/1/oa_18016.pdfTest; http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-18016-5Test; https://epub.ub.uni-muenchen.de/18016Test/ |
| DOI: | 10.1136/oem.2009.048785 |
| الإتاحة: | https://doi.org/10.1136/oem.2009.048785Test https://epub.ub.uni-muenchen.de/18016/1/oa_18016.pdfTest https://epub.ub.uni-muenchen.de/18016Test/ http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-18016-5Test |
| حقوق: | This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively |
| رقم الانضمام: | edsbas.2234EE3B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/oem.2009.048785 |
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