Immediate Delivery Compared With Expectant Management in Late Preterm Prelabor Rupture of Membranes
| العنوان: | Immediate Delivery Compared With Expectant Management in Late Preterm Prelabor Rupture of Membranes |
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| المؤلفون: | Christine Willekes, Lisa M. Askie, Annemijn A. de Ruigh, Vincenzo Berghella, David Espinoza, Johanna Quist-Nelson, Jillian A. Patterson, Eva Pajkrt, Ben W.J. Mol, David P. van der Ham, Anna Lene Seidler, Jonathan M. Morris |
| المساهمون: | APH - Health Behaviors & Chronic Diseases, APH - Quality of Care, APH - Personalized Medicine, ARD - Amsterdam Reproduction and Development, Obstetrics and Gynaecology, Other departments |
| المصدر: | Obstetrics and gynecology, 131(2), 269-279. Lippincott Williams and Wilkins Obstetrics & Gynecology |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, Fetal Membranes, Premature Rupture, BIRTH, Prom, TERM, Infant, Newborn, Diseases, SUBTYPES, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, medicine, Late preterm, Rupture of membranes, Humans, 030212 general & internal medicine, 11 Medical and Health Sciences, Expectant management, 030219 obstetrics & reproductive medicine, SEPSIS, business.industry, Obstetrics, Individual participant data, INDUCTION, Infant, Newborn, DEATH, Obstetrics and Gynecology, WEEKS GESTATIONAL-AGE, medicine.disease, Delivery, Obstetric, PREMATURE RUPTURE, TRIALS, Meta-analysis, Gestation, Female, business, CHILDREN BORN |
| الوصف: | OBJECTIVE: To compare the effects of immediate delivery an expectant management among women whose pregnancies were complicated by preterm prelabor rupture of membranes (PROM) in the late preterm period (from 34 0/7 weeks until 36 6/7 weeks of gestation). DATA SOURCES: PubMed, Scopus, ClinicalTrials.gov, EMBASE, and the Cochrane Central Register of Controlled Trials were searched from inception until December 2016. METHODS OF STUDY SELECTION: We included all randomized controlled trials with individual participant data reporting on late preterm PROM with randomization to immediate delivery or expectant management. The primary outcome was a composite of adverse neonatal outcomes: probable or definitive neonatal sepsis, necrotizing enterocolitis, respiratory distress syndrome, stillbirth, or neonatal death. TABULATION, INTEGRATION AND RESULTS: Of eight eligible trials (total n=3,203 mothers), three (2,563 mothers, 2,572 neonates) had individual participant data available. The composite adverse neonatal outcome occurred in 9.6% of neonates in the immediate delivery group and 8.3% in the expectant management group (relative risk [RR] 1.20, 95% CI 0.94-1.55). Neonatal sepsis rates were 2.6% and 3.5%, respectively (RR 0.74, 95% CI 0.47-1.15). Neonates in the immediate delivery group were more likely to be diagnosed with respiratory distress syndrome (RR 1.47, 95% CI 1.10-1.97), and to be admitted to the neonatal intensive care unit or special care nursery (RR 1.17, 95% CI 1.11-1.23) and had longer admissions. Mothers randomized to immediate delivery were less likely to have an antepartum hemorrhage (RR 0.57, 95% CI 0.34-0.95) or chorioamnionitis (RR 0.21, 95% CI 0.13-0.35), but more likely to undergo cesarean delivery (RR 1.26, 95% CI 1.08-1.47). CONCLUSION: In women with late preterm PROM, immediate delivery and expectant management resulted in comparable rates of the composite of adverse neonatal outcomes. Effects on individual secondary maternal and neonatal outcomes were mixed. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, 42016032972. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0029-7844 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed5298036510f150a88cb55661fdd58Test https://doi.org/10.1097/aog.0000000000002447Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4ed5298036510f150a88cb55661fdd58 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00297844 |
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