Effects of Fat and Protein Preloads on Pouch Emptying, Intestinal Transit, Glycaemia, Gut Hormones, Glucose Absorption, Blood Pressure and Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass
| العنوان: | Effects of Fat and Protein Preloads on Pouch Emptying, Intestinal Transit, Glycaemia, Gut Hormones, Glucose Absorption, Blood Pressure and Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass |
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| المؤلفون: | Christopher K. Rayner, Carly M. Burgstad, Dylan Bartholomeusz, Judith M. Wishart, Max Bellon, Gary A. Wittert, Scott Standfield, Melissa Neo, Nam Q. Nguyen, Tamara L. Debreceni, Michael Horowitz |
| المصدر: | Obesity Surgery. 26:77-84 |
| بيانات النشر: | Springer Science and Business Media LLC, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Gastric Bypass, Incretin, Hemodynamics, Blood Pressure, 030209 endocrinology & metabolism, Type 2 diabetes, Glucagon, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Heart Rate, Internal medicine, Humans, Insulin, Medicine, Gastrointestinal Transit, Nutrition and Dietetics, business.industry, digestive, oral, and skin physiology, Area under the curve, Water, Nausea, Middle Aged, medicine.disease, Dietary Fats, Preload, Endocrinology, Female, 030211 gastroenterology & hepatology, Surgery, Dumping syndrome, Dietary Proteins, business |
| الوصف: | The aim was to determine the effects of fat and protein preloads on pouch emptying (PE), caecal arrival time (CAT), glucose absorption, blood glucose (BSL), gut hormones, haemodynamics and gastrointestinal (GI) symptoms in subjects who had undergone Roux-en-Y gastric bypass (RYGB) >12 months previously. Ten RYGB subjects were studied on three occasions, in randomised order, receiving 200-ml preloads of either water, fat (30 ml olive oil) or whey protein (55 g), 30 min before a mixed meal. PE, CAT, BSL, plasma 3-O-methyl-D-glucopyranose (3-OMG), insulin, glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide 1 (GLP-1) and glucagon, blood pressure (BP), heart rate (HR) and GI symptoms were assessed over 270 min. Although fat and protein preloads did not alter PE of either solids or liquids, the CAT of solids, but not liquids, was longer than that after the water preload (fat 68 ± 5 min and protein 71 ± 6 min vs. water 46 ± 5 min; P = 0.02). BSL elevated promptly after the meal on all days (P |
| تدمد: | 1708-0428 0960-8923 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a503a0fd192ad04cc972e979e10ce9Test https://doi.org/10.1007/s11695-015-1722-7Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....f1a503a0fd192ad04cc972e979e10ce9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17080428 09608923 |
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