التفاصيل البيبلوغرافية
| العنوان: |
Association Between Cardiorespiratory Fitness and Risk of Type 2 Diabetes: A Meta-Analysis. |
| المؤلفون: |
Qiu, Shanhu, Cai, Xue, Yang, Bingquan, Du, Ziwei, Cai, Min, Sun, Zilin, Zügel, Martina, Michael Steinacker, Jürgen, Schumann, Uwe |
| المصدر: |
Obesity (19307381); Feb2019, Vol. 27 Issue 2, p315-324, 10p |
| مصطلحات موضوعية: |
TYPE 2 diabetes, PHYSICAL activity, PHYSICAL fitness, CARDIOVASCULAR diseases, BODY mass index |
| مستخلص: |
Objective: This meta-analysis aimed to (1) quantify the association of cardiorespiratory fitness (CRF) with type 2 diabetes risk in the general population and statin users and (2) investigate the joint effects of CRF and fatness with type 2 diabetes risk.Methods: Databases were searched for cohort studies reporting the association between CRF and type 2 diabetes risk. Summary hazard ratios (HRs) were obtained using random-effects models.Results: Fifteen studies were included. The HRs of type 2 diabetes for every 1-metabolic equivalent increase in CRF were 0.90 (95% CI: 0.86-0.94) for the general population and 0.92 (95% CI: 0.87-0.97) for statin users, and the HRs were linearly shaped (both Pnonlinearity > 0.40). Compared with the nonstatin cohort, there was an increased risk of type 2 diabetes in statin users with the lowest and moderate CRF categories, but this was not present in the highest CRF category. The HR of type 2 diabetes for overweight/obesity-fit category versus normal weight-fit category was larger than that of the normal weight-unfit category versus the normal weight-fit category (Pinteraction = 0.004).Conclusions: There was an inverse and dose-dependent association between CRF and type 2 diabetes risk. High CRF may eliminate the diabetogenic effect from statins, yet decreased body weight index seems superior in preventing type 2 diabetes. [ABSTRACT FROM AUTHOR] |
|
Copyright of Obesity (19307381) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder