Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
| العنوان: | Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study |
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| المؤلفون: | Stanislava Kolouskova, Zdenek Sumnik, Jan Vosahlo, Lukas Plachy, Petra Konečná, Vit Neuman, Stepanka Pruhova, Martina Romanova, Marketa Pavlikova, Jana Vyzralkova, Barbora Obermannova, Lenka Petruzelkova |
| المصدر: | Nutrients Volume 13 Issue 11 Nutrients, Vol 13, Iss 3903, p 3903 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, Percentile, endocrine system diseases, Body height, type 1 diabetes, Hypoglycemia, Article, Body Mass Index, Diet, Carbohydrate-Restricted, low-carbohydrate diet, Surveys and Questionnaires, Internal medicine, medicine, Humans, TX341-641, Child, Low carbohydrate, Glycated Hemoglobin, Type 1 diabetes, Nutrition and Dietetics, medicine.diagnostic_test, Nutrition. Foods and food supply, business.industry, Body Weight, medicine.disease, Lipids, Body Height, Diabetes Mellitus, Type 1, Blood pressure, Multi center study, time in range, Female, Lipid profile, business, Food Science |
| الوصف: | Aims/hypothesis: The proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data. Methods: Caregivers of 1040 children with T1D from three centers were addressed with a structured questionnaire regarding the children’s carbohydrate intake and experience with LCD (daily energy intake from carbohydrates below 26% of age-recommended values). The subjects currently on LCD were compared to a group of non-LCD respondents matched to age, T1D duration, sex, type and center of treatment. Results: A total of 624/1040 (60%) of the subjects completed the survey. A total of 242/624 (39%) subjects reported experience with voluntary carbohydrate restriction with 36/624 (5.8%) subjects currently following the LCD. The LCD group had similar HbA1c (45 vs. 49.5, p = 0.11), lower average glycemia (7.0 vs. 7.9, p = 0.02), higher time in range (74 vs. 67%, p = 0.02), lower time in hyperglycemia > 10 mmol/L (17 vs. 20%, p = 0.04), tendency to more time in hypoglycemia < 3.9 mmol/L(8 vs. 5%, p = 0.05) and lower systolic blood pressure percentile (43 vs. 74, p = 0.03). The groups did not differ in their lipid profile nor in current body height, weight or BMI. The LCD was mostly initiated by the parents or the subjects themselves and only 39% of the families consulted their decision with the diabetologist. Conclusions/interpretation: Low carbohydrate diet is not scarce in children with T1D and is associated with modestly better disease control. At the same time, caution should be applied as it showed a tendency toward more frequent hypoglycemia. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| DOI: | 10.3390/nu13113903 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3595d4dd4bd8ee513dda68625082f3f3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3595d4dd4bd8ee513dda68625082f3f3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726643 |
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| DOI: | 10.3390/nu13113903 |