CARCINOEMBRYONIC ANTIGEN (CEA) IN HEAD AND NECK TUMORS
| العنوان: | CARCINOEMBRYONIC ANTIGEN (CEA) IN HEAD AND NECK TUMORS |
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| المؤلفون: | Satoshi Ogino |
| المصدر: | Nippon Jibiinkoka Gakkai Kaiho. 80:334-343 |
| بيانات النشر: | Oto-Rhino-Laryngological Society of Japan, Inc., 1977. |
| سنة النشر: | 1977 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pathology, biology, business.industry, Head and neck tumors, medicine.disease, Gastroenterology, digestive system diseases, Metastasis, Titer, Carcinoembryonic antigen, Otorhinolaryngology, Nasopharyngeal carcinoma, Internal medicine, medicine, Carcinoma, biology.protein, Adenocarcinoma, Stage (cooking), business, neoplasms |
| الوصف: | The level of carcinoembryonic antigen (CEA) in the plasma was measured by the CEA assay system established by Hansen et al. in 91 patients, consisting of 73 patients with head and neck carcinomas, 7 with malignant lymphomas, 3 with Wegener's granulomatosis, and 8 with head and neck benign tumors. The plasma CEA level higher than 5.0 ng/ml was estimated positive and 15 of 28 (53%) laryngeal carcinoma patients, 8 of 13 (62%) maxillary carcinoma patients, and one of 8 (12%) nasopharyngeal carcinoma patients were positive. In total, 34 of 73 (47%) head and neck carcinoma patients had an abnormally elevated CEA level, whereas only one of 7 (14%) malignant lymphoma patients, and none of 8 patients who had benign tumors had positive CEA level. There was no significant difference in the plasma CEA level between the patients with adenocarcinoma and those with squamous cell carcinomas. The patients of the advanced stage who had metastasis of the cervical lymphonodi and/or the other organs showed significantly higher CEA level than those of the earlier stage. It was also found that the CEA titer dropped after successful therapies, but elevated again with the reccurrence of tumors. It seems that repeated CEA determination is a valuable means for assessment of the effect of the therapies and necessary in follow-up to tumors. |
| تدمد: | 1883-0854 0030-6622 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::36ee06f4d8c420b76982d99c5a8cc1c7Test https://doi.org/10.3950/jibiinkoka.80.334Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........36ee06f4d8c420b76982d99c5a8cc1c7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18830854 00306622 |
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