CsF-promoted carboxylation of aryl(hetaryl) terminal alkynes with atmospheric CO2 at room temperature
| العنوان: | CsF-promoted carboxylation of aryl(hetaryl) terminal alkynes with atmospheric CO2 at room temperature |
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| المؤلفون: | Zhimin Liu, Yunxing Zhao, Pingfang Yang, Biao Yu, Zhang Huinian, Zhenzhen Yang, Xue-Wang Gao |
| المصدر: | New Journal of Chemistry. 41:9250-9255 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Propiolic acid, 010405 organic chemistry, Aryl, Substrate (chemistry), General Chemistry, 010402 general chemistry, 01 natural sciences, Trimethylsilylacetylene, Catalysis, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Carboxylation, Functional group, Materials Chemistry, Organic chemistry |
| الوصف: | A CsF-promoted carboxylation of aryl(hetaryl) terminal alkynes with atmospheric CO2 in the presence of trimethylsilylacetylene was developed to give functionalized propiolic acid products at room temperature. A wide range of propiolic acids bearing functional groups was successfully obtained in good to excellent yields. Mechanistic studies demonstrate that in the carboxylation process the alkynylsilane intermediate was first in situ generated, which was then trapped by CO2, giving rise to the corresponding functionalized propiolic acids after acidification. The advantages of this approach include avoiding use of transition-metal catalysts, wide substrate scope together with excellent functional group tolerance, ambient conditions and a facile work-up procedure. |
| تدمد: | 1369-9261 1144-0546 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::793972fbb7d90be763b79cb36549670aTest https://doi.org/10.1039/c7nj01779kTest |
| رقم الانضمام: | edsair.doi...........793972fbb7d90be763b79cb36549670a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13699261 11440546 |
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