التفاصيل البيبلوغرافية
العنوان: |
Lenalidomide plus Dexamethasone for High-Risk Smoldering Multiple Myeloma. |
المؤلفون: |
Mateos, María-Victoria1, Hernández, Miguel-Teodoro2, Giraldo, Pilar3, de la Rubia, Javier, de Arriba, Felipe4, López Corral, Lucía1, Rosiñol, Laura5, Paiva, Bruno1, Palomera, Luis6, Bargay, Joan7, Oriol, Albert8, Prosper, Felipe, López, Javier9, Olavarría, Eduardo10, Quintana, Nuria, García, José-Luis, Bladé, Joan5, Lahuerta, Juan-José11, San Miguel, Jesús-F.1 sanmiguel@usal.es |
المصدر: |
New England Journal of Medicine. 8/1/2013, Vol. 369 Issue 5, p438-447. 10p. 1 Diagram, 3 Charts, 1 Graph. |
مصطلحات موضوعية: |
*MULTIPLE myeloma treatment, *CANCER treatment, *DEXAMETHASONE, *DRUG efficacy, *THERAPEUTICS research |
مستخلص: |
The article discusses the results of a phase 3, randomized trial that examined the efficacy of induction therapy with lenalidomide and dexamethasone, followed by maintenance therapy with lenalidomide, in patients with high-risk smoldering multiple myeloma. Findings showed the progression to active disease is delayed with early treatment for patients with high-risk smoldering myeloma. It also shows that early treatment increases overall survival. |
قاعدة البيانات: |
Academic Search Index |