التفاصيل البيبلوغرافية
| العنوان: |
New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. |
| المؤلفون: |
Katona, Cornelius L.1 c.katona@ucl.ac.uk, Katona, Cara P.2 |
| المصدر: |
Neuropsychiatric Disease & Treatment. 2014, Vol. 10, p349-354. 6p. |
| مصطلحات موضوعية: |
*SEROTONIN, *MENTAL depression, *SEROTONIN receptors, *NEUROTRANSMITTER receptors, *NEUROPSYCHIATRY |
| مستخلص: |
Vortioxetine is a novel antidepressant with effects on multiple 5-HT receptors and on the serotonin transporter. This paper reviews preclinical and clinical evidence regarding its mechanism of action, its tolerability, and its efficacy in treating major depression. Clinical studies indicate that vortioxetine is effective in the treatment of major depression, though there is no suggestion of superiority over active comparators. There may be a clinically meaningful advantage in terms of tolerability. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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