التفاصيل البيبلوغرافية
| العنوان: |
The pathogenesis of Chiari I malformation and syringomyelia. |
| المؤلفون: |
Sekula Jr, Raymond F, Arnone, Gregory D, Crocker, Christine, Aziz, Khaled M, Alperin, Noam |
| المصدر: |
Neurological Research; Apr2011, Vol. 33 Issue 3, p232-239, 8p, 4 Black and White Photographs, 1 Chart |
| مستخلص: |
Objective: The pathogeneses of Chiari malformation type I and syringomyelia are incompletely understood. In this article, the authors attempt to review the current theories on the pathogeneses of Chiari I malformation and syringomyelia. Methods: A literature review for articles pertaining to Chiari I malformation or syringomyelia before August 2010 was conducted; in addition, the author's own experience in treating Chiari I malformation and syringomyelia is included. Results: Chiari I malformation has been defined radiographically as cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum. By this narrow definition, Chiari I malformation (i.e. cerebellar tonsillar herniation or ectopia 5 mm or greater below the foramen magnum) likely encompasses a heterogeneous grouping of disorders caused by different mechanisms. Molecular and genetic studies have been helpful in furthering our understanding of Chiari I malformation. Conclusion: A review of the pathogeneses of Chiari I malformation and syringomyelia is reported. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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