State and trait characteristics of anterior insula time-varying functional connectivity
| العنوان: | State and trait characteristics of anterior insula time-varying functional connectivity |
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| المؤلفون: | Yann Cobigo, Bruce L. Miller, Isabel E. Allen, Jesse A. Brown, Virginia E. Sturm, Giovanni Battistella, William W. Seeley, Suzanne M. Shdo, Jersey Deng, Katarzyna Kurcyus, Joel H. Kramer, Howard H. Rosen, Gianina Toller, Maria Luisa Gorno-Tempini, Adam M. Staffaroni, Alex G. Lee, Lorenzo Pasquini, Valentina Borghesani, Katherine P. Rankin |
| المصدر: | NeuroImage NeuroImage, Vol 208, Iss, Pp 116425-(2020) |
| بيانات النشر: | Elsevier BV, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, Trait, Datasets as Topic, Medical and Health Sciences, 0302 clinical medicine, 80 and over, Cluster Analysis, Longitudinal Studies, Time-varying functional connectivity, media_common, Aged, 80 and over, Cerebral Cortex, 0303 health sciences, Anterior insula, Functional connectivity, 05 social sciences, food and beverages, Cognition, Middle Aged, Magnetic Resonance Imaging, ddc, Psychosocial Functioning, Neurology, Neurological, Female, Psychology, State, Adult, 1.1 Normal biological development and functioning, Cognitive Neuroscience, media_common.quotation_subject, Sensory system, Empathy, Emotional processing, Basic Behavioral and Social Science, Article, 050105 experimental psychology, lcsh:RC321-571, Young Adult, 03 medical and health sciences, Underpinning research, Clinical Research, Behavioral and Social Science, Connectome, Humans, 0501 psychology and cognitive sciences, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, Aged, Socio-emotional functioning, Neurology & Neurosurgery, Psychology and Cognitive Sciences, Neurosciences, State (functional analysis), Cross-Sectional Studies, Neuroscience, 030217 neurology & neurosurgery |
| الوصف: | The human anterior insula (aINS) is a topographically organized brain region, in which ventral portions contribute to socio-emotional function through limbic and autonomic connections, whereas the dorsal aINS contributes to cognitive processes through frontal and parietal connections. Open questions remain, however, regarding how aINS connectivity varies over time. We implemented a novel approach combining seed-to-whole-brain sliding-window functional connectivity MRI and k-means clustering to assess time-varying functional connectivity of aINS subregions. We studied three independent large samples of healthy participants and longitudinal datasets to assess inter- and intra-subject stability, and related aINS time-varying functional connectivity profiles to dispositional empathy. We identified four robust aINS time-varying functional connectivity modes that displayed both “state” and “trait” characteristics: while modes featuring connectivity to sensory regions were modulated by eye closure, modes featuring connectivity to higher cognitive and emotional processing regions were stable over time and related to empathy measures. |
| وصف الملف: | application/pdf |
| تدمد: | 1053-8119 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcce514522a81e9d8aa80818dc460cc1Test https://doi.org/10.1016/j.neuroimage.2019.116425Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bcce514522a81e9d8aa80818dc460cc1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10538119 |
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