دورية
Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients.
العنوان: | Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients. |
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المؤلفون: | Tarnow, L, Grarup, N, Hansen, T, Parving, H H, Pedersen, O |
المصدر: | Nephrology Dialysis Transplantation; August 2001, Vol. 16 Issue: 8 p1653-1656, 4p |
مستخلص: | An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma cell differentiating antigen (PC-1), a specific inhibitor of insulin receptor signalling, has been reported to predict a faster progression of nephropathy in Italian and British type 1 diabetic patients. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 09310509 14602385 |
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DOI: | 10.1093/ndt/16.8.1653 |