دورية أكاديمية
Fibrinogen-to-albumin ratio is related to the severity of coronary artery disease in chronic kidney disease patients undergoing coronary angiography
| العنوان: | Fibrinogen-to-albumin ratio is related to the severity of coronary artery disease in chronic kidney disease patients undergoing coronary angiography |
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| المؤلفون: | Li-Hua Lin, Hong Liu, Dong-Hua Jin, Jun Zou, Yu-Xian Xie, Hong Qiu, Miao Jia, Da-Mei Li, Bi-Cheng Liu |
| المصدر: | Nefrología (English Edition), Vol 42, Iss 6, Pp 696-703 (2022) |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Relación fibrinógeno/albúmina, Enfermedad arterial coronaria, Estenosis de la arteria coronaria, Enfermedad renal crónica, Angiografía coronaria, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Objectives: This study was to explore the potential relationship between the fibrinogen-to-albumin ratio (FAR) and the presence and severity of coronary artery disease (CAD) in stage 3–5 predialysis chronic kidney disease (CKD) patients. Design: This study included 978 patients undergoing coronary angiography (CAG). CAD was defined as the presence of obstructive stenosis > 50% of the lumen diameter in any of the four main coronary arteries. Gensini scores (GSs), left main coronary artery (LMCA) and three-vessel coronary artery disease (TVD) were used to elevate the severity of CAD. Results: The adjusted odds ratios of CAD were 3.059 (95% CI: 1.859–5.032) and 2.670 (95% CI: 1.605–4.441) in the third and fourth quartiles of FAR compared with the first quartile, respectively. Among 759 patients diagnosed with CAD, multivariate logistic regression analysis showed that FAR (at the 0.01 level) was significantly positively associated with the presence of LMCA (adjusted OR = 1.177, 95% CI 1.067–1.299, P = 0.001) or TVD (adjusted OR = 1.154, 95% CI 1.076–1.238, P < 0.001), and a higher GS (adjusted OR = 1.152, 95% CI 1.073–1.238, P < 0.001). Conclusions: FAR levels were independently associated with the presence and severity of CAD in stage 3–5 predialysis CKD patients. Resumen: Objetivos: Este estudio pretendía explorar la relación potencial entre la relación fibrinógeno/albúmina (FAR) y la presencia y la gravedad de la enfermedad arterial coronaria (EAC) en pacientes con enfermedad renal crónica (ERC) en estadio 3-5 en la etapa prediálisis. Diseño: Este estudio incluyó a 978 pacientes tratados mediante angiografía coronaria. La EAC se definió como la presencia de estenosis obstructiva > 50% del diámetro de la luz de cualquiera de las 4 arterias coronarias principales. Se utilizaron las puntuaciones de Gensini (GS), la enfermedad de la arteria coronaria izquierda (EACI) y la EAC de 3 vasos (ETV) para evaluar la gravedad de la EAC. Resultados: Los cocientes de posibilidades de EAC fueron 3,059 (IC del 95%: ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2013-2514 |
| العلاقة: | http://www.sciencedirect.com/science/article/pii/S2013251422001201Test; https://doaj.org/toc/2013-2514Test; https://doaj.org/article/1e3d9b8df10740dfa26e1a4b12bca9d0Test |
| DOI: | 10.1016/j.nefroe.2022.11.010 |
| الإتاحة: | https://doi.org/10.1016/j.nefroe.2022.11.010Test https://doaj.org/article/1e3d9b8df10740dfa26e1a4b12bca9d0Test |
| رقم الانضمام: | edsbas.3513C364 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20132514 |
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| DOI: | 10.1016/j.nefroe.2022.11.010 |