التفاصيل البيبلوغرافية
| العنوان: |
Molecular targets for cancer chemoprevention. |
| المؤلفون: |
William Jr., William N., Heymach, John V., Kim, Edward S., Lippman, Scott M., William, William N Jr |
| المصدر: |
Nature Reviews Drug Discovery; Mar2009, Vol. 8 Issue 3, p213-225, 13p, 4 Diagrams, 3 Charts |
| مصطلحات موضوعية: |
CHEMOPREVENTION, CANCER treatment, VACCINES, PAPILLOMAVIRUSES, LIVER cancer, BREAST cancer |
| مستخلص: |
Vaccines targeting infections with hepatitis B virus, a risk factor for hepatocellular cancer, and human papillomavirus, a risk factor for cervical cancer, are considered major clinical cancer chemoprevention successes. Molecularly targeted agents can prevent breast cancer (raloxifene and tamoxifen), colorectal adenomas (celecoxib), and prostate cancer (finasteride). Nevertheless, the broad translation of chemoprevention to the clinic is not yet a reality. Continuing research of molecular targets promises to expand the reach of chemoprevention and to personalize it as well. [ABSTRACT FROM AUTHOR] |
|
Copyright of Nature Reviews Drug Discovery is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
