Clonal haematopoiesis induces a pro-inflammatory monocyte phenotype in HF
| العنوان: | Clonal haematopoiesis induces a pro-inflammatory monocyte phenotype in HF |
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| المؤلفون: | Gregory B. Lim |
| المصدر: | Nature Reviews Cardiology. 18:74-74 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, business.industry, Disease progression, Inflammatory monocyte, 030204 cardiovascular system & hematology, medicine.disease, Phenotype, Transcriptome, 03 medical and health sciences, Haematopoiesis, 030104 developmental biology, 0302 clinical medicine, Heart failure, embryonic structures, Mutation (genetic algorithm), Immunology, medicine, In patient, Cardiology and Cardiovascular Medicine, business |
| الوصف: | In patients with heart failure who are carriers of a clonal haematopoiesis driver mutation in DNMT3A, circulating monocytes have a pro-inflammatory transcriptome, which might worsen disease progression. |
| تدمد: | 1759-5010 1759-5002 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::c3f86e8a343d6321c2e770590cba281fTest https://doi.org/10.1038/s41569-020-00481-5Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........c3f86e8a343d6321c2e770590cba281f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17595010 17595002 |
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