Competition for iron drives phytopathogen control by natural rhizosphere microbiomes
| العنوان: | Competition for iron drives phytopathogen control by natural rhizosphere microbiomes |
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| المؤلفون: | Qirong Shen, Xiaofang Wang, Alexandre Jousset, Zhengying Shao, Jos Kramer, Zhong Wei, Rolf Kümmerli, Tianjie Yang, Ville-Petri Friman, Kehao Cao, Shaohua Gu, Yangchun Xu, Xinlan Mei, Mei Li |
| المساهمون: | University of Zurich, Wei, Zhong, Xu, Yangchun, Ecology and Biodiversity, Sub Ecology and Biodiversity |
| المصدر: | Nature Microbiology Nature Microbiology, 5(8), 1002. Nature Publishing Group Nat Microbiol |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Siderophore, Bacterial/genetics, Siderophores, medicine.disease_cause, Applied Microbiology and Biotechnology, Plant Roots, 2726 Microbiology (medical), 1307 Cell Biology, Soil, 10126 Department of Plant and Microbial Biology, Solanum lycopersicum, RNA, Ribosomal, 16S, Plant Roots/microbiology, Pathogen, Phylogeny, Soil Microbiology, media_common, Soil/chemistry, 2. Zero hunger, 0303 health sciences, Rhizosphere, Ralstonia solanacearum, RNA, Ribosomal, 16S/genetics, Ralstonia solanacearum/isolation & purification, biology, Microbiota, 2404 Microbiology, food and beverages, Plants, Plant Diseases/microbiology, DNA, Bacterial/genetics, Host-Pathogen Interactions, Sequence Analysis, 16S/genetics, Microbiology (medical), DNA, Bacterial, media_common.quotation_subject, Iron, Immunology, 610 Medicine & health, Infections, Microbiology, Article, Competition (biology), Bacterial genetics, 03 medical and health sciences, 1311 Genetics, Genetics, medicine, 2402 Applied Microbiology and Biotechnology, Humans, Microbiome, 030304 developmental biology, Plant Diseases, Ribosomal, 2403 Immunology, 030306 microbiology, Lycopersicon esculentum/metabolism, Pathogenic bacteria, DNA, Cell Biology, Sequence Analysis, DNA, biology.organism_classification, 13. Climate action, RNA, 11493 Department of Quantitative Biomedicine, Iron/metabolism |
| الوصف: | Plant pathogenic bacteria cause high crop and economic losses to human societies1-3. Infections by such pathogens are challenging to control as they often arise through complex interactions between plants, pathogens and the plant microbiome4,5. Experimental studies of this natural ecosystem at the microbiome-wide scale are rare, and consequently we have a poor understanding of how the taxonomic and functional microbiome composition and the resulting ecological interactions affect pathogen growth and disease outbreak. Here, we combine DNA-based soil microbiome analysis with in vitro and in planta bioassays to show that competition for iron via secreted siderophore molecules is a good predictor of microbe-pathogen interactions and plant protection. We examined the ability of 2,150 individual bacterial members of 80 rhizosphere microbiomes, covering all major phylogenetic lineages, to suppress the bacterium Ralstonia solanacearum, a global phytopathogen capable of infecting various crops6,7. We found that secreted siderophores altered microbiome-pathogen interactions from complete pathogen suppression to strong facilitation. Rhizosphere microbiome members with growth-inhibitory siderophores could often suppress the pathogen in vitro as well as in natural and greenhouse soils, and protect tomato plants from infection. Conversely, rhizosphere microbiome members with growth-promotive siderophores were often inferior in competition and facilitated plant infection by the pathogen. Because siderophores are a chemically diverse group of molecules, with each siderophore type relying on a compatible receptor for iron uptake8-12, our results suggest that pathogen-suppressive microbiome members produce siderophores that the pathogen cannot use. Our study establishes a causal mechanistic link between microbiome-level competition for iron and plant protection and opens promising avenues to use siderophore-mediated interactions as a tool for microbiome engineering and pathogen control. |
| وصف الملف: | application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf |
| تدمد: | 2058-5276 1740-1526 |
| DOI: | 10.1038/s41564-020-0719-8 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de911c0f86884798c9ede51f5b95ebb1Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....de911c0f86884798c9ede51f5b95ebb1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20585276 17401526 |
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| DOI: | 10.1038/s41564-020-0719-8 |