Detecting overlapping protein complexes in protein-protein interaction networks
| العنوان: | Detecting overlapping protein complexes in protein-protein interaction networks |
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| المؤلفون: | Tamás Nepusz, Haiyuan Yu, Alberto Paccanaro |
| المصدر: | Nature Methods. 9:471-472 |
| بيانات النشر: | Springer Science and Business Media LLC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Genetics, Saccharomyces cerevisiae Proteins, Saccharomyces genome database, Systems biology, Saccharomyces cerevisiae, Cell Biology, Computational biology, Information center, Biology, biology.organism_classification, Biochemistry, Article, Protein protein interaction network, Protein sequencing, Protein Interaction Mapping, Cluster Analysis, Protein Interaction Maps, Cluster analysis, Molecular Biology, Algorithms, Protein Interaction Map, Biotechnology |
| الوصف: | We introduce clustering with overlapping neighborhood expansion (ClusterONE), a method for detecting potentially overlapping protein complexes from protein-protein interaction data. ClusterONE-derived complexes for several yeast data sets showed better correspondence with reference complexes in the Munich Information Center for Protein Sequence (MIPS) catalog and complexes derived from the Saccharomyces Genome Database (SGD) than the results of seven popular methods. The results also showed a high extent of functional homogeneity. |
| تدمد: | 1548-7105 1548-7091 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09f8c16929b83213c18544a260d032eTest https://doi.org/10.1038/nmeth.1938Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c09f8c16929b83213c18544a260d032e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15487105 15487091 |
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