التفاصيل البيبلوغرافية
العنوان: |
Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA. |
المؤلفون: |
Nardone, Julie1, Lee, Dong U.2, Ansel, K. Mark1, Rao, Anjana1 arao@cbr.med.harvard.edu |
المصدر: |
Nature Immunology. Aug2004, Vol. 5 Issue 8, p768-774. 7p. 1 Diagram, 2 Graphs. |
مصطلحات موضوعية: |
*BIOINFORMATICS, *GENETIC research, *GENETIC regulation, *GENOMICS, *GENETICS |
مستخلص: |
Discusses how to integrate biological and bioinformatic methods in the discovery of gene regulatory regions, and includes a tutorial on widely available comparative genomics programs. Assumptions which underlie the utility of comparative genomic analyses for discovery of regulatory regions; Steps in finding conserved noncoding sequences regions; Factors determining which species should be compared. |
قاعدة البيانات: |
Academic Search Index |