دورية أكاديمية

Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA.

التفاصيل البيبلوغرافية
العنوان: Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA.
المؤلفون: Nardone, Julie1, Lee, Dong U.2, Ansel, K. Mark1, Rao, Anjana1 arao@cbr.med.harvard.edu
المصدر: Nature Immunology. Aug2004, Vol. 5 Issue 8, p768-774. 7p. 1 Diagram, 2 Graphs.
مصطلحات موضوعية: *BIOINFORMATICS, *GENETIC research, *GENETIC regulation, *GENOMICS, *GENETICS
مستخلص: Discusses how to integrate biological and bioinformatic methods in the discovery of gene regulatory regions, and includes a tutorial on widely available comparative genomics programs. Assumptions which underlie the utility of comparative genomic analyses for discovery of regulatory regions; Steps in finding conserved noncoding sequences regions; Factors determining which species should be compared.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:15292908
DOI:10.1038/ni0804-768