التفاصيل البيبلوغرافية
العنوان:
SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself
المؤلفون:
Marta Ferreira-Gomes , Andrey Kruglov , Pawel Durek , Frederik Heinrich , Caroline Tizian , Gitta Anne Heinz , Anna Pascual-Reguant , Weijie Du , Ronja Mothes , Chaofan Fan , Stefan Frischbutter , Katharina Habenicht , Lisa Budzinski , Justus Ninnemann , Peter K. Jani , Gabriela Maria Guerra , Katrin Lehmann , Mareen Matz , Lennard Ostendorf , Lukas Heiberger , Hyun-Dong Chang , Sandy Bauherr , Marcus Maurer , Günther Schönrich , Martin Raftery , Tilmann Kallinich , Marcus Alexander Mall , Stefan Angermair , Sascha Treskatsch , Thomas Dörner , Victor Max Corman , Andreas Diefenbach , Hans-Dieter Volk , Sefer Elezkurtaj , Thomas H. Winkler , Jun Dong , Anja Erika Hauser , Helena Radbruch , Mario Witkowski , Fritz Melchers , Andreas Radbruch , Mir-Farzin Mashreghi
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Our understanding on the humoral immunity induced by SARS-CoV-2 is still lacking. Here the authors analyze B cell responses at the single cell level to find that, in severe COVID-19 patients, plasmablasts shift from IFN to TGFβ instruction to produce IgA antibodies that are not specific to dominant SARS-CoV-2 antigens.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-021-22210-3
الوصول الحر:
https://doaj.org/article/58a67a60b8ae4622829438abe4d63e7cTest
رقم الانضمام:
edsdoj.58a67a60b8ae4622829438abe4d63e7c
قاعدة البيانات:
Directory of Open Access Journals
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