Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis

التفاصيل البيبلوغرافية
العنوان:	Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
المؤلفون:	Eric Letouzé, Jayendra Shinde, Victor Renault, Gabrielle Couchy, Jean-Frédéric Blanc, Emmanuel Tubacher, Quentin Bayard, Delphine Bacq, Vincent Meyer, Jérémy Semhoun, Paulette Bioulac-Sage, Sophie Prévôt, Daniel Azoulay, Valérie Paradis, Sandrine Imbeaud, Jean-François Deleuze, Jessica Zucman-Rossi
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Tumorigenesis is a complex process driven by numerous risk factors. Here, genomic analysis of liver cancer reveals the evolution of mutational signatures during tumor development, highlighting mutational and structural signatures linked to environmental exposures and endogenous cellular processes.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
العلاقة:	https://doaj.org/toc/2041-1723Test
DOI:	10.1038/s41467-017-01358-x
الوصول الحر:	https://doaj.org/article/a2db6282c9e94e1b953a8aca7a20d3f7Test
رقم الانضمام:	edsdoj.2db6282c9e94e1b953a8aca7a20d3f7
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-017-01358-x