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المؤلفون: Lisa S. Kearns, Helena Liang, Nona Farbehi, Xikun Han, Alex W. Hewitt, Drew Neavin, Grace E. Lidgerwood, Stuart MacGregor, M Isabel G Lopez Sanchez, Lerna Gulluyan, Damián Hernández, David A. Mackey, Angela Steinmann, Linda Clarke, Vivek Gupta, Louise A. Rooney, Joseph E. Powell, Alice Pébay, Chia-Ling Chan, Robyn H. Guymer, Ran Zhang, Joao A. Paulo, Maciej Daniszewski, Guy Bylsma, Uyen Nguyen, Vikkitharan Gnanasambandapillai, Rachael Zekanovic, Anne Senabouth, Nitin Verma, Mehdi Mirzaei
المصدر: Nature communications. 13(1)
مصطلحات موضوعية: Genetics, Proteomics, Multidisciplinary, Retinal pigment epithelium, Neurodegeneration, General Physics and Astronomy, General Chemistry, Retinal Pigment Epithelium, Biology, Macular degeneration, Quantitative trait locus, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Transcriptome, Macular Degeneration, medicine.anatomical_structure, Geographic Atrophy, Expression quantitative trait loci, medicine, Humans, sense organs, Induced pluripotent stem cell
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49df11c858c66f28265e3899aa36f2d7Test
https://pubmed.ncbi.nlm.nih.gov/35882847Test -
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المؤلفون: S.E. Moroi, Christopher J Hammond, Peter Kraft, Terri L. Young, Tin Aung, Unnar Thorsteinsdottir, R. Rand Allingham, Francesca Pasutto, Murray H. Brilliant, Robert P. Igo, Joel S. Schuman, Paul R. Lichter, Adriana I. Iglesias Gonzalez, Jessica N. Cooke Bailey, Jonathan L. Haines, Chiea Chuen Khor, Robert Ritch, René Hoehn, John H. Fingert, Puya Gharahkhani, Terry Gaasterland, Calvin C P Pang, Cheng Yu Cheng, Louis R. Pasquale, Lisa A Hark, Andrew J. Lotery, Douglas Vollrath, Yutao Liu, David A. Mackey, Stuart MacGregor, William K. Scott, Pirro G. Hysi, Alex W. Hewitt, Jae H. Kang, Cornelia M. van Duijn, Arthur J. Sit, Margaret A. Pericak-Vance, Michael A. Hauser, Peter Bonnemaijer, Veronique Vitart, Kuldev Singh, D. L. Budenz, Doaa Nabih Maria, Gudmar Thorleifsson, Julia R. Richards, Kari Stefansson, Sumana R Chintalapudi, Doug Rhee, Richard K. Lee, Anthony P Khawaja, Anthony Realini, Robert W. Williams, Eranga N. Vithana, Gadi Wollstein, Fridbert Jonansson, Jamie E Craig, Xiang Di Wang, Tanja Zeller, Douglas E. Gaasterland, Donald J. Zack, Caroline C W Klaver, Janey L. Wiggs, Monica M. Jablonski
المساهمون: Psychiatry, Epidemiology, Clinical Genetics, Ophthalmology
المصدر: Chintalapudi, S R, Maria, D, Di Wang, X, Bailey, J N C, Allingham, R, Brilliant, M, Budenz, D, Fingert, J, Gaasterland, D, Gaasterland, T, Haines, J L, Hark, L, Hauser, M, Igo, R, Hee Kang, J, Kraft, P, Lee, R, Lichter, P, Liu, Y, Moroi, S, Pasquale, L R, Pericak-Vance, M, Realini, A, Rhee, D, Richards, J R, Ritch, R, Schuman, J, Scott, W K, Singh, K, Sit, A, Vollrath, D, Wollstein, G, Zack, D, Aung, T, Bonnemaijer, P, Cheng, C Y, Craig, J, Van Duijn, C, Gharahkhani, P, Iglesias Gonzalez, A, Hammond, C J, Hewitt, A, Hoehn, R, Jonansson, F, Khawaja, A, Chuen Khor, C, Klaver, C C W, Lotery, A, MacKey, D, MacGregor, S, Pang, C, Pasutto, F, Stefansson, K, Thorleifsson, G, Thorsteinsdottir, U, Vitart, V, Vithana, E, Young, T, Zeller, T, Hysi, P G, Wiggs, J L, Williams, R W & Jablonski, M M 2017, ' Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility ', Nature Communications, vol. 8, no. 1, 1755 . https://doi.org/10.1038/s41467-017-00837-5Test
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications, 8(1):1755. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Male, Intraocular pressure, Candidate gene, genetic structures, General Physics and Astronomy, Glaucoma, Genome-wide association study, Disease, Bioinformatics, Cohort Studies, Mice, 0302 clinical medicine, lcsh:Science, Multidisciplinary, biology, 3. Good health, Mice, Inbred DBA, CACNA2D1, Female, Glaucoma, Open-Angle, Open angle glaucoma, Science, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Genetic variation, medicine, Animals, Humans, Genetic Predisposition to Disease, Intraocular Pressure, Aged, business.industry, General Chemistry, medicine.disease, eye diseases, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, 030221 ophthalmology & optometry, biology.protein, lcsh:Q, Calcium Channels, sense organs, business, Genome-Wide Association Study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b10ace24e0c92bcd94cc63b53e0738fTest
http://www.scopus.com/inward/record.url?scp=85035018930&partnerID=8YFLogxKTest -
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المؤلفون: Shea Ping Yip, Patrick Y. P. Kao, Fumihiko Matsuda, Hideo Nakanishi, Maria Schache, Tien Yin Wong, Satoshi Morooka, Kyoko Ohno-Matsui, Ozen Polasek, Kenji Yamashiro, Akitaka Tsujikawa, Zhenglin Yang, Chiea Chuen Khor, E-Shyong Tai, Norimoto Gotoh, Yumiko Akagi-Kurashige, Peng Chen, Stuart MacGregor, David A. Mackey, Isao Nakata, Alan F. Wright, Akira Meguro, Seang-Mei Saw, Maurice Yap, Fan Qiao, Yasuharu Tabara, Paul N. Baird, Muka Moriyama, Caroline Hayward, Ching-Yu Cheng, Luling Huang, Andrea J. Richardson, Nobuhisa Mizuki, Veronique Vitart, Yi Shi, Alex W. Hewitt, Sentaro Kusuhara, Tin Aung, Harry Campbell, Kim Hung Leung, Masaki Takeuchi, Gabriel Cuellar, Kenji Suda, Masahiro Miyake, Ryo Yamada, Nagahisa Yoshimura
المصدر: Miyake, M, Yamashiro, K, Tabara, Y, Suda, K, Morooka, S, Nakanishi, H, Khor, C-C, Chen, P, Qiao, F, Nakata, I, Akagi-Kurashige, Y, Gotoh, N, Tsujikawa, A, Meguro, A, Kusuhara, S, Polasek, O, Hayward, C, Wright, A F, Campbell, H, Richardson, A J, Schache, M, Takeuchi, M, Mackey, D A, Hewitt, A W, Cuellar, G, Shi, Y, Huang, L, Yang, Z, Leung, K H, Kao, P Y P, Yap, M K H, Yip, S P, Moriyama, M, Ohno-Matsui, K, Mizuki, N, MacGregor, S, Vitart, V, Aung, T, Saw, S-M, Tai, E-S, Wong, T Y, Cheng, C-Y, Baird, P N, Yamada, R & Matsuda, F & Yoshimura, N 2015, ' Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia ', Nature Communications, vol. 6, 6689 . https://doi.org/10.1038/ncomms7689Test
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, genetic structures, Adolescent, Genotype, General Physics and Astronomy, Animals, Asian Continental Ancestry Group, Cohort Studies, Cornea, Disease Models, Animal, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Humans, Immunohistochemistry, Mice, Middle Aged, Myopia, Polymorphism, Single Nucleotide, Proto-Oncogene Proteins, Retina, RNA, Messenger, Severity of Illness Index, Wnt Proteins, Young Adult, Genome-wide association study, General Biochemistry, Genetics and Molecular Biology, White People, Asian People, Polymorphism (computer science), Ophthalmology, Severity of illness, medicine, Young adult, Multidisciplinary, business.industry, General Chemistry, Odds ratio, eye diseases, medicine.anatomical_structure, Choroidal neovascularization, sense organs, medicine.symptom, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c98516bbd4611cfefdd1d755849650Test
https://pubmed.ncbi.nlm.nih.gov/25823570Test -
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المؤلفون: Nicholas G. Martin, René Höhn, Nagahisa Yoshimura, Jonathan H. Lass, Ilkka Seppälä, Masahiro Miyake, Kay-Tee Khaw, Pirro G. Hysi, Rhys Fogarty, Yi Lu, Zoran Vatavuk, Cécile Delcourt, Andrew D. Paterson, John P. Kemp, Jeremy A. Guggenheim, Jaakko Kaprio, Robert P. Igo, James F. Wilson, Stuart MacGregor, Anthony P Khawaja, Beate St Pourcain, Margaret M. DeAngelis, Jing Hua Zhao, Cornelia M. van Duijn, Olavi Pärssinen, Terho Lehtimäki, Roger W. Beuerman, Leslie J. Raffel, Eranga N. Vithana, Caroline Hayward, Cathy Williams, Thomas Meitinger, Lei Zhou, Candice E H Ho, Ozren Polasek, Hoi Suen Wong, Jie Jin Wang, Nicholas J. Timpson, Norbert Pfeiffer, Toomas Haller, Akira Meguro, Wei Chen, Ching-Yu Cheng, Vishal Jhanji, Johannes R. Vingerling, Mika Kähönen, Puya Gharahkhani, Sheng Feng, Nobuhisa Mizuki, Maurice Yap, Katie M Williams, Vincent Tan, Paul Mitchell, Taina Rantanen, Sudha K. Iyengar, Seang-Mei Saw, Christopher J Hammond, Kathryn P. Burdon, Harry Campbell, Sarayut Janmahasatian, Andres Metspalu, Caroline C W Klaver, Jugnoo S Rahi, Kenji Yamashiro, Laura Portas, Céline Bellenguez, Igor Rudan, Robert Luben, Virginie J. M. Verhoeven, Mary Frances Cotch, Paul N. Baird, Qiao Fan, Najaf Amin, David A. Mackey, Jenifer E. Huffman, Emily Y. Chew, Veluchamy A. Barathi, Tien Yin Wong, Ronald Klein, Jeremy Fondran, Mario Pirastu, Alan F. Wright, Jamie E Craig, Brian W Fleck, Paul J. Foster, Alvin L. Young, Alex W. Hewitt, Tin Aung, Maurizio Fossarello, Kari-Matti Mäkelä, Tanja Zeller, Maria Blettner, Xu Wang, Eileen Tai-Hui Boh, Terri L. Young, Mingguang He, Joan E. Bailey Wilson, Olli T. Raitakari, Shea Ping Yip, M. Kamran Ikram, Seyhan Yazar, Albert Hofman, Alireza Mirshahi, Tae Hwi Schwantes-An, Charumathi Sabanayagam, Pancy O. S. Tam, Ginevra Biino, Xiaobo Guo, Angela Döring, Audrey Cougnard-Gregoire, David M. Evans, Xiaohui Li, Christian Gieger, Songhomitra Panda-Jonas, Jost B. Jonas, Jan Willem L Tideman, Maria Schache, Chi Pui Pang, Barbara E.K. Klein, Simona Vaccargiu, Veronique Vitart, Jing Xie, Claire L. Simpson, S. Mohsen Hosseini, Chiea Chuen Khor, Dwight Stambolian, E. Shyong Tai, Xiangtian Zhou, Li Jia Chen, Milly S. Tedja, Margaux A. Morrison, Janina S. Ried, Yik Ying Teo, Konrad Oexle, Robert Wojciechowski, Nicholas J. Wareham, André G. Uitterlinden, Peter K. Joshi, Ya Xing Wang, Jean-François Korobelnik, George McMahon, Vinay Nangia, Elisabeth M. van Leeuwen, Lindsay A. Farrer, Preeti Gupta, Johanna Mazur, Evelin Mihailov, Wan’E. Lim, George Davey Smith, Liang Xu, Rosalynn Grace Siantar, Juho Wedenoja, Cristina Venturini, Fernando Rivadeneira
المساهمون: Clinicum, Department of Public Health, Silmäklinikka, Jaakko Kaprio / Principal Investigator, Institute for Molecular Medicine Finland, Genetic Epidemiology, Consortium for Refractive Error and Myopia (CREAM), Clinical Genetics, Erasmus MC other, Epidemiology, Internal Medicine, Ophthalmology, Obstetrics & Gynecology
المصدر: Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Höhn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimäki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K M, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, Mcmahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-an, T, Igo, R P, Mirshahi, A, Cougnard-gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kähönen, M, Seppala, I, Zeller, T, Meitinger, T, Ried, J S, Gieger, C, Portas, L, Van Leeuwen, E M, Amin, N, Uitterlinden, A G, Rivadeneira, F, Hofman, A, Vingerling, J R, Wang, Y X, Wang, X, Tai-hui Boh, E, Ikram, M K, Sabanayagam, C, Gupta, P, Tan, V, Zhou, L, Ho, C E H, Lim, W, Beuerman, R W, Siantar, R, Tai, E, Vithana, E, Mihailov, E, Khor, C, Hayward, C, Luben, R N, Foster, P J, Klein, B E K, Klein, R, Wong, H, Mitchell, P, Metspalu, A, Aung, T, Young, T L, He, M, Pärssinen, O, Van Duijn, C M, Jin Wang, J, Williams, C, Jonas, J B, Teo, Y, Mackey, D A, Oexle, K, Yoshimura, N, Paterson, A D, Pfeiffer, N, Wong, T, Baird, P N, Stambolian, D, Wilson, J E B, Cheng, C, Hammond, C J, Klaver, C C W, Saw, S, Rahi, J S, Korobelnik, J, Kemp, J P, Timpson, N J, Smith, G D, Craig, J E, Burdon, K P, Fogarty, R D, Iyengar, S K, Chew, E, Janmahasatian, S, Martin, N G, Macgregor, S, Xu, L, Schache, M, Nangia, V, Panda-jonas, S, Wright, A F, Fondran, J R, Lass, J H, Feng, S, Zhao, J H, Khaw, K, Wareham, N J, Rantanen, T, Kaprio, J, Pang, C P, Chen, L J, Tam, P O, Jhanji, V, Young, A L, Döring, A, Raffel, L J, Cotch, M, Li, X, Yip, S P, Yap, M K H, Biino, G, Vaccargiu, S, Fossarello, M, Fleck, B, Yazar, S, Tideman, J W L, Tedja, M, Deangelis, M M, Morrison, M, Farrer, L, Zhou, X, Chen, W, Mizuki, N, Meguro, A & Mäkelä, K M 2016, ' Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, pp. 11008 . https://doi.org/10.1038/ncomms11008Test
Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Hohn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimaki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K M, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, McMahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-An, T H, Igo, R P, Mirshahi, A, Cougnard-Gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kahonen, M, Seppala, I, Zeller, T, Meitinger, T, Ried, J S, Gieger, C, Portas, L, Van Leeuwen, E M, Amin, N, Uitterlinden, A G, Rivadeneira, F, Hofman, A, Vingerling, J R, Wang, Y X, Wang, X, Tai-Hui Boh, E, Ikram, M K, Sabanayagam, C, Gupta, P, Tan, V, Zhou, L, Ho, C E H, Lim, WE, Beuerman, R W, Siantar, R, Tai, E S, Vithana, E, Mihailov, E, Khor, C C, Hayward, C, Luben, R N, Foster, P J, Klein, B E K, Klein, R, Wong, H S, Mitchell, P, Metspalu, A, Aung, T, Young, T L, He, M, Parssinen, O, Van Duijn, C M, Jin Wang, J, Williams, C, Jonas, J B, Teo, Y Y, MacKey, D A, Oexle, K, Yoshimura, N, Paterson, A D, Pfeiffer, N, Wong, T Y, Baird, P N, Stambolian, D, Wilson, J E B, Cheng, C-Y, Hammond, C J, Klaver, C C W, Saw, S M, Rahi, J S, Korobelnik, J F, Kemp, J P, Timpson, N J, Smith, G D, Craig, J E, Burdon, K P, Fogarty, R D, Iyengar, S K, Chew, E, Janmahasatian, S, Martin, N G, MacGregor, S, Xu, L, Schache, M, Nangia, V, Panda-Jonas, S, Wright, A F, Fondran, J R, Lass, J H, Feng, S, Zhao, J H, Khaw, K T, Wareham, N J, Rantanen, T, Kaprio, J, Pang, C P, Chen, L J, Tam, P O, Jhanji, V, Young, A L, Doring, A, Raffel, L J, Cotch, M F, Li, X, Yip, S P, Yap, M K H, Biino, G, Vaccargiu, S, Fossarello, M, Fleck, B, Yazar, S, Tideman, J W L, Tedja, M, Deangelis, M M, Morrison, M, Farrer, L, Zhou, X, Chen, W, Mizuki, N, Meguro, A & Makela, K M 2016, ' Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, 11008 . https://doi.org/10.1038/ncomms11008Test
Nature Communications, 7, 11008
Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Höhn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimäki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, McMahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-An, T-H, Igo, R P, Mirshahi, A, Cougnard-Gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kähönen, M, Seppala, I, Zeller, T, Meitinger, T, Zhou, L, Mitchell, P, Hammond, C J 2016, ' Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, 11008 . https://doi.org/10.1038/ncomms11008Test
Nature Communications
Nature Communications, 7, pp. 11008
Nat. Commun. 7:11008 (2016)
Fan, Qiao; Verhoeven, Virginie J M; Wojciechowski, Robert; Barathi, Veluchamy A; Hysi, Pirro G; Guggenheim, Jeremy A; Höhn, René; Vitart, Veronique; Khawaja, Anthony P; Yamashiro, Kenji; Hosseini, S Mohsen; Lehtimäki, Terho; Lu, Yi; Haller, Toomas; Xie, Jing; Delcourt, Cécile; Pirastu, Mario; Wedenoja, Juho; Gharahkhani, Puya; Venturini, Cristina; ... (2016). Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature communications, 7(11008), p. 11008. Nature Publishing Group 10.1038/ncomms11008 <http://dx.doi.org/10.1038/ncomms11008Test>
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, 7. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Refractive error, genetic structures, General Physics and Astronomy, Genome-wide association study, VARIANTS, refractive error, gene, EYE, Bioinformatics, INCIDENT MYOPIA, Genome-wide association studies, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], 0302 clinical medicine, Polymorphism (computer science), 10. No inequality, POPULATION, education.field_of_study, Multidisciplinary, ACTIVATED PROTEIN-KINASE, ta3142, single-nucleotide polymorphism, RETINAL-PIGMENT EPITHELIUM, OUTDOOR ACTIVITY, 3142 Public health care science, environmental and occupational health, 3. Good health, Refractive errors, Meta-analysis, loci, Educational Status, Science, Population, 610 Medicine & health, Environment, Biology, ta3111, Polymorphism, Single Nucleotide, Article, White People, General Biochemistry, Genetics and Molecular Biology, Education, 03 medical and health sciences, Asian People, SDG 3 - Good Health and Well-being, Genetic variation, medicine, Humans, SNP, Genetic Predisposition to Disease, myopia, 3125 Otorhinolaryngology, ophthalmology, education, RECEPTOR, Gene Expression Profiling, ta1184, General Chemistry, Heritability, medicine.disease, eye diseases, ta3125, TIME OUTDOORS, 030104 developmental biology, Genetic Loci, Evolutionary biology, RISK-FACTORS, 030221 ophthalmology & optometry, RE, sense organs, 3111 Biomedicine, Genome-Wide Association Study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17851d314c7a84aed54df51a46e69004Test
https://doi.org/10.1038/ncomms11008Test