التفاصيل البيبلوغرافية
العنوان:
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
المؤلفون:
Puya Gharahkhani , Eric Jorgenson , Pirro Hysi , Anthony P. Khawaja , Sarah Pendergrass , Xikun Han , Jue Sheng Ong , Alex W. Hewitt , Ayellet V. Segrè , John M. Rouhana , Andrew R. Hamel , Robert P. Igo , Helene Choquet , Ayub Qassim , Navya S. Josyula , Jessica N. Cooke Bailey , Pieter W. M. Bonnemaijer , Adriana Iglesias , Owen M. Siggs , Terri L. Young , Veronique Vitart , Alberta A. H. J. Thiadens , Juha Karjalainen , Steffen Uebe , Ronald B. Melles , K. Saidas Nair , Robert Luben , Mark Simcoe , Nishani Amersinghe , Angela J. Cree , Rene Hohn , Alicia Poplawski , Li Jia Chen , Shi-Song Rong , Tin Aung , Eranga Nishanthie Vithana , NEIGHBORHOOD consortium , ANZRAG consortium , Biobank Japan project , FinnGen study , UK Biobank Eye and Vision Consortium , GIGA study group , and Me Research Team , Gen Tamiya , Yukihiro Shiga , Masayuki Yamamoto , Toru Nakazawa , Hannah Currant , Ewan Birney , Xin Wang , Adam Auton , Michelle K. Lupton , Nicholas G. Martin , Adeyinka Ashaye , Olusola Olawoye , Susan E. Williams , Stephen Akafo , Michele Ramsay , Kazuki Hashimoto , Yoichiro Kamatani , Masato Akiyama , Yukihide Momozawa , Paul J. Foster , Peng T. Khaw , James E. Morgan , Nicholas G. Strouthidis , Peter Kraft , Jae H. Kang , Chi Pui Pang , Francesca Pasutto , Paul Mitchell , Andrew J. Lotery , Aarno Palotie , Cornelia van Duijn , Jonathan L. Haines , Chris Hammond , Louis R. Pasquale , Caroline C. W. Klaver , Michael Hauser , Chiea Chuen Khor , David A. Mackey , Michiaki Kubo , Ching-Yu Cheng , Jamie E. Craig , Stuart MacGregor , Janey L. Wiggs
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk loci and mapping effects across multiple ethnicities.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-020-20851-4
الوصول الحر:
https://doaj.org/article/ea46188f0f2c4f0cae58f959caf971a2Test
رقم الانضمام:
edsdoj.46188f0f2c4f0cae58f959caf971a2
قاعدة البيانات:
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