نتائج البحث

1

TGF-β-induced DACT1 Biomolecular Condensates Repress Wnt Signaling To Promote Bone Metastasis

المؤلفون: Hannah Slabodkin, Clifford P. Brangwynne, Christina DeCoste, Yibin Kang, Dan Bracha, Yong Wei, Nana Park, Mark Esposito, Cao Fang, Ramesh T. Gunaratna, Ileana M. Cristea, Chiara Spadazzi, Katelyn C. Cook, Gary Laevsky

المصدر: Nature cell biology

مصطلحات موضوعية: Male, TGF-β, Phase separation, Mice, Nude, Bone Neoplasms, Breast Neoplasms, Mice, SCID, Article, DACT1, 03 medical and health sciences, Wnt, 0302 clinical medicine, breast cancer, Cell Movement, Mice, Inbred NOD, Transforming Growth Factor beta, Cell Line, Tumor, Wnt3A Protein, Animals, Humans, biomolecular condensates, Neoplasm Invasiveness, Casein Kinase II, Wnt Signaling Pathway, Adaptor Proteins, Signal Transducing, Cell Proliferation, 030304 developmental biology, bone metastasis, 0303 health sciences, Chemistry, Activator (genetics), HEK 293 cells, Wnt signaling pathway, Nuclear Proteins, Prostatic Neoplasms, Signal transducing adaptor protein, Cell Biology, liquid-liquid phase separation, Hedgehog signaling pathway, Cell biology, Gene Expression Regulation, Neoplastic, Wnt Proteins, Crosstalk (biology), HEK293 Cells, Cytoplasm, 030220 oncology & carcinogenesis, Female, Casein kinase 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b507a41d4c60ad15e3bed9f7ff6302Test
http://europepmc.org/articles/PMC7970447Test

2

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

المصدر: Nature cell biology
U221
Acosta, J C, Banito, A, Wuestefeld, T, Georgilis, A, Janich, P, Morton, J P, Athineos, D, Kang, T-W, Lasitschka, F, Andrulis, M, Pascual, G, Morris, K J, Khan, S, Jin, H, Dharmalingam, G, Snijders, A P, Carroll, T, Capper, D, Pritchard, C, Inman, G J, Longerich, T, Sansom, O J, Benitah, S A, Zender, L & Gil, J 2013, ' A complex secretory program orchestrated by the inflammasome controls paracrine senescence ', Nature Cell Biology, vol. 15, no. 8, pp. 978-90 . https://doi.org/10.1038/ncb2784Test
Recercat. Dipósit de la Recerca de Catalunya
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مصطلحات موضوعية: Inflammasomes, NF-KAPPA-B, Cèl·lules -- Envelliment, SASP, Mice, TUMOR PROGRESSION, 11 Medical and Health Sciences, Cellular Senescence, paracrine, Inflammasome, TGF-BETA, Immunohistochemistry, PANCREATIC-CANCER, Cell biology, Gene Expression Regulation, Neoplastic, Cell Aging, Colonic Neoplasms, Models, Animal, IL-1α, GROWTH, Signal transduction, Cell aging, Life Sciences & Biomedicine, medicine.drug, Protein Binding, Signal Transduction, Senescence, EXPRESSION, Paracrine Communication, Biology, Article, Transforming Growth Factor beta1, Paracrine signalling, TGFβ, P16(INK4A), inflammasome, Cell Line, Tumor, TGF beta signaling pathway, medicine, DIPLOID CELL STRAINS, TUMORIGENESIS, Animals, Humans, Senolytic, Tumors, P53, Science & Technology, fungi, Cell Biology, 06 Biological Sciences, secretome, Interleukin-1, Developmental Biology