A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas
| العنوان: | A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas |
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| المؤلفون: | P. Hutin, I. Stoll, Paul Basset, Jean-Pierre Bellocq, Pierre Chambon, J. M. Limacher, Osvaldo L. Podhajcer, Chenard Mp, Catherine Wolf, M. C. Rio |
| المصدر: | Nature. 348:699-704 |
| بيانات النشر: | Springer Science and Business Media LLC, 1990. |
| سنة النشر: | 1990 |
| مصطلحات موضوعية: | Stromal cell, Molecular Sequence Data, Gene Expression, Breast Neoplasms, Biology, Extracellular matrix, Matrix Metalloproteinase 11, Gene expression, Humans, Amino Acid Sequence, Northern blot, Cloning, Molecular, Matrilysin, Growth Substances, skin and connective tissue diseases, Gene, Metalloproteinase, Multidisciplinary, Base Sequence, Metalloendopeptidases, Nucleic Acid Hybridization, DNA, Fibroblasts, Embryo, Mammalian, Molecular biology, Extracellular Matrix, Cancer research, RNA, Tetradecanoylphorbol Acetate, Immunohistochemistry, Female |
| الوصف: | A gene has been identified that is expressed specifically in stromal cells surrounding invasive breast carcinomas. On the basis of its sequence, the product of this gene, named stromelysin-3, is a new member of the family of metalloproteinase enzymes which degrade the extracellular matrix. The suggestion is that stromelysin-3 is one of the stroma-derived factors that have long been postulated to play an important part in progression of epithelial malignancies. |
| تدمد: | 1476-4687 0028-0836 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084f0d311d9c6025558bf550522e8984Test https://doi.org/10.1038/348699a0Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....084f0d311d9c6025558bf550522e8984 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14764687 00280836 |
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