المؤلفون: Bose, Rohit, Karthaus, Wouter R, Armenia, Joshua, Abida, Wassim, Iaquinta, Phillip J, Zhang, Zeda, Wongvipat, John, Wasmuth, Elizabeth V, Shah, Neel, Sullivan, Patrick S, Doran, Michael G, Wang, Ping, Patruno, Anna, Zhao, Yilin, International SU2C/PCF Prostate Cancer Dream Team, Zheng, Deyou, Schultz, Nikolaus, Sawyers, Charles L

المصدر: Nature. 546(7660)

مصطلحات موضوعية: International SU2C/PCF Prostate Cancer Dream Team, Prostate, Cell Line, Tumor, Animals, Humans, Mice, Prostatic Neoplasms, Serine Endopeptidases, Tumor Suppressor Proteins, Receptors, Androgen, Repressor Proteins, Androgens, Signal Transduction, Up-Regulation, Mutation, Genes, Male, Proto-Oncogene Proteins c-ets, Protein Stability, Transcriptome, Carcinogenesis, Transcriptional Regulator ERG, Cell Line, Tumor, Receptors, Androgen, MD Multidisciplinary, General Science & Technology

الوصول الحر: https://escholarship.org/uc/item/6z25z7n0Test

المؤلفون: Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu Chang, Xiaoju Wang, Yuping Zhang, Josh N. Vo, Steven Kregel, Stephanie A. Simko, Andrew D. Delekta, Mustapha Jaber, Heng Zheng, Ingrid J. Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Zelenka-Wang, Sanjita Sasmal, Leena Khare, Subhendu Mukherjee, Chandrasekhar Abbineni, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey I. Nesvizhskii, Rohit Mehra, Ulka Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan

المصدر: Nature

مصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, Male, cells, genetic processes, Genes, myc, Chromatin remodelling, macromolecular substances, Article, Targeted therapies, Transcriptional Regulator ERG, Nitriles, Phenylthiohydantoin, Animals, Humans, Adenosine Triphosphatases, Multidisciplinary, Prostate cancer, DNA Helicases, Nuclear Proteins, Prostatic Neoplasms, Oncogenes, Xenograft Model Antitumor Assays, enzymes and coenzymes (carbohydrates), Enhancer Elements, Genetic, Receptors, Androgen, Benzamides, biological phenomena, cell phenomena, and immunity, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792ceed7ffa9433eeb3a2a771d4d4aaTest
http://europepmc.org/articles/PMC8770127Test

المؤلفون: McDonald, Thomas V, Yu, Zhihui, Ming, Zhen, Palma, Eugen, Meyers, Marian B, Wang, Ke-Wei, Goldstein, Steve AN, Fishman, Glenn I

المصدر: Nature. 388(6639)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Genetics, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Aetiology, Underpinning research, Animals, CHO Cells, Cation Transport Proteins, Cricetinae, DNA-Binding Proteins, ERG1 Potassium Channel, Electrophysiology, Epitopes, Ether-A-Go-Go Potassium Channels, Hemagglutinins, Humans, Ion Channel Gating, Myocardium, Potassium Channels, Potassium Channels, Voltage-Gated, Protein Binding, Proto-Oncogene Proteins c-myc, Recombinant Fusion Proteins, Trans-Activators, Transcriptional Regulator ERG, Transfection, Xenopus, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4sq7h1bcTest

المؤلفون: Patrick S. Sullivan, Michael G. Doran, Charles L. Sawyers, Ping Wang, Neel Shah, Phillip J. Iaquinta, Wassim Abida, Anna Patruno, Elizabeth V. Wasmuth, Nikolaus Schultz, John Wongvipat, Rohit Bose, Joshua Armenia, Wouter R. Karthaus, Yilin Zhao, Zeda Zhang, Deyou Zheng

المصدر: Nature, vol 546, iss 7660
Bose, Rohit; Karthaus, Wouter R; Armenia, Joshua; Abida, Wassim; Iaquinta, Phillip J; Zhang, Zeda; et al.(2017). ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.. Nature, 546(7660), 671-675. doi: 10.1038/nature22820. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6z25z7n0Test

مصطلحات موضوعية: Male, 0301 basic medicine, genetic structures, Carcinogenesis, medicine.disease_cause, Androgen, Mice, Prostate cancer, Receptors, Cancer, Genetics, Mutation, Tumor, Multidisciplinary, biology, Protein Stability, Serine Endopeptidases, Prostate, food and beverages, Up-Regulation, Receptors, Androgen, Androgens, Erg, Signal Transduction, General Science & Technology, Cell Line, 03 medical and health sciences, Transcriptional Regulator ERG, Cell Line, Tumor, MD Multidisciplinary, medicine, Animals, Humans, PTEN, Transcription factor, Proto-Oncogene Proteins c-ets, Tumor Suppressor Proteins, fungi, Prostatic Neoplasms, medicine.disease, eye diseases, Repressor Proteins, Androgen receptor, 030104 developmental biology, Genes, International SU2C/PCF Prostate Cancer Dream Team, biology.protein, Cancer research, sense organs, Transcriptome, Chromatin immunoprecipitation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2b9658302f5569bee182eae43cd17eTest
https://doi.org/10.1038/nature22820Test

المؤلفون: Patricia Sousa, Areum Han, Sergei Doulatov, Deepak Kumar Jha, Scott B. Snapper, Yi Fen Lu, Ryohichi Sugimura, Clara Soria-Valles, Erik Serrao, George Q. Daley, R. Grant Rowe, Andrea Ditadi, Alan Engelman, Ted N. Zhu, Edroaldo Lummertz da Rocha, Gordon Keller, Jeremy A. Goettel, Irene Wong, Mohan Malleshaiah

المصدر: Nature. 545:432-438

مصطلحات موضوعية: Pluripotent Stem Cells, 0301 basic medicine, Myeloid, Cellular differentiation, Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Transcriptional Regulator ERG, Proto-Oncogene Proteins, medicine, Animals, Humans, Cell Lineage, Endothelium, Progenitor cell, Induced pluripotent stem cell, Homeodomain Proteins, Multidisciplinary, Hematopoietic Stem Cell Transplantation, Cell Differentiation, Cellular Reprogramming, Hematopoietic Stem Cells, 3. Good health, Cell biology, Repressor Proteins, Endothelial stem cell, Haematopoiesis, Homeobox A10 Proteins, 030104 developmental biology, medicine.anatomical_structure, RUNX1, chemistry, Core Binding Factor Alpha 2 Subunit, Immunology, Trans-Activators, Female, Stem cell, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd619e343a6dda4d8a312d21b0a6556Test
https://doi.org/10.1038/nature22370Test

المؤلفون: Lei Wang, Xiaojun Jing, Rajal B. Shah, Bo Han, Bharathi Laxman, Xuhong Cao, Beth E. Helgeson, Rohit Mehra, Arul M. Chinnaiyan, Jindan Yu, Scott A. Tomlins, Qi Cao, Kenneth J. Pienta, Sooryanarayana Varambally, James E. Montie, Anjana Menon, Saravana M. Dhanasekaran, David S. Morris, Mark A. Rubin, Diane Roulston

المصدر: Nature. 448:595-599

مصطلحات موضوعية: Genetics, Multidisciplinary, Gene rearrangement, Chromoplexy, Biology, urologic and male genital diseases, medicine.disease_cause, medicine.disease, TMPRSS2, ETV1, Prostate cancer, LNCaP, medicine, Cancer research, Carcinogenesis, Transcriptional Regulator ERG

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a1d37fcad126ee18a2bc626c9acde97eTest
https://doi.org/10.1038/nature06024Test

المؤلفون: Anuradha Gopalan, Jennifer Tran, Arkaitz Carracedo-Perez, Caterina Nardella, Pier Paolo Pandolfi, Carlos Cordon-Cardo, William L. Gerald, Andrea Alimonti, Zhenbang Chen, Peter T. Scardino, Brett S. Carver

المصدر: Nature. 457(7231)

مصطلحات موضوعية: Male, Oncogene Proteins, Fusion, Gene Expression, Mice, Transgenic, Biology, medicine.disease_cause, TMPRSS2, Polymerase Chain Reaction, ETV1, Article, Translocation, Genetic, Proto-Oncogene Protein c-ets-1, Prostate cancer, Mice, Transcriptional Regulator ERG, Prostate, Cell Line, Tumor, medicine, Humans, Animals, Genetics, Chromosome Aberrations, Oncogene Proteins, Multidisciplinary, Prostatic Neoplasms, Chromoplexy, Oncogenes, medicine.disease, DNA-Binding Proteins, medicine.anatomical_structure, Cell Transformation, Neoplastic, Cancer research, Disease Progression, Carcinogenesis, Erg, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c316878f4850150e5a48900b084550c0Test
https://pubmed.ncbi.nlm.nih.gov/17671502Test

المؤلفون: Ke-Wei Wang, Steve A.N. Goldstein, Zhihui Yu, Thomas V. McDonald, Glenn I. Fishman, Marian B. Meyers, Zhen Ming, Eugen C. Palma

المصدر: Europe PubMed Central

مصطلحات موضوعية: ERG1 Potassium Channel, medicine.medical_specialty, Potassium Channels, Recombinant Fusion Proteins, Xenopus, hERG, CHO Cells, Transfection, Proto-Oncogene Proteins c-myc, Epitopes, Transcriptional Regulator ERG, Cricetinae, biology.animal, Internal medicine, medicine, Animals, Humans, KvLQT1, Mink, Cation Transport Proteins, Ion channel, Multidisciplinary, biology, Myocardium, KCNE2, KCNE3, KCNE4, Ether-A-Go-Go Potassium Channels, Potassium channel, Cell biology, DNA-Binding Proteins, Electrophysiology, Hemagglutinins, Endocrinology, Potassium Channels, Voltage-Gated, Trans-Activators, biology.protein, Ion Channel Gating, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e04bf817c9afde2102ad64413df45e9Test
https://doi.org/10.1038/40882Test

المؤلفون: Michel Lazdunski, Eric Guillemare, Florian Lesage, Georges Romey, Michel Fink, Jacques Barhanin

المصدر: Nature. 384:78-80

مصطلحات موضوعية: ERG1 Potassium Channel, medicine.medical_specialty, Potassium Channels, Xenopus, Molecular Sequence Data, hERG, Transfection, Sudden death, Cell Line, Mice, Transcriptional Regulator ERG, Internal medicine, medicine, Animals, Humans, Point Mutation, Repolarization, Amino Acid Sequence, KvLQT1, Cloning, Molecular, Cation Transport Proteins, Multidisciplinary, KCNQ Potassium Channels, Sequence Homology, Amino Acid, biology, Chemistry, Myocardium, KCNE2, KCNE3, KCNE4, medicine.disease, Molecular biology, Ether-A-Go-Go Potassium Channels, Romano–Ward syndrome, DNA-Binding Proteins, Endocrinology, Potassium Channels, Voltage-Gated, COS Cells, KCNQ1 Potassium Channel, Potassium, Trans-Activators, biology.protein, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38745174f21e02edac993f14124aa38Test
https://doi.org/10.1038/384078a0Test

المؤلفون: Paula Smith, Gary Yellen, Thomas Baukrowitz

المصدر: Nature. 379(6568)

مصطلحات موضوعية: ERG1 Potassium Channel, Potassium Channels, hERG, Gating, Pharmacology, Cell Line, Membrane Potentials, Transcriptional Regulator ERG, Potassium Channel Blockers, Repolarization, Animals, Drosophila Proteins, Humans, Magnesium, Cation Transport Proteins, Multidisciplinary, biology, Myocardium, Conductance, Tetraethylammonium, Arrhythmias, Cardiac, Tetraethylammonium Compounds, Transmembrane protein, Potassium channel, Ether-A-Go-Go Potassium Channels, Recombinant Proteins, DNA-Binding Proteins, Electrophysiology, Long QT Syndrome, Potassium Channels, Voltage-Gated, Mutation, biology.protein, Biophysics, Shaker Superfamily of Potassium Channels, Trans-Activators, Drosophila, Ion Channel Gating

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0b276fd651a319ae3e6da07333f5f1Test
https://pubmed.ncbi.nlm.nih.gov/8587597Test