المؤلفون: Billesbølle, Christian B, Azumaya, Caleigh M, Kretsch, Rachael C, Powers, Alexander S, Gonen, Shane, Schneider, Simon, Arvedson, Tara, Dror, Ron O, Cheng, Yifan, Manglik, Aashish

المصدر: Nature. 586(7831)

مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, Digestive Diseases, Liver Disease, Hematology, Underpinning research, 1.1 Normal biological development and functioning, Apoproteins, Binding Sites, Cation Transport Proteins, Cobalt, Cryoelectron Microscopy, Hepcidins, Homeostasis, Humans, Iron, Molecular Dynamics Simulation, Protein Domains, Proteolysis, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/77g2k8b4Test

المؤلفون: Jarred W. Rensvold, Evgenia Shishkova, Yuriy Sverchkov, Ian J. Miller, Arda Cetinkaya, Angela Pyle, Mateusz Manicki, Dain R. Brademan, Yasemin Alanay, Julian Raiman, Adam Jochem, Paul D. Hutchins, Sean R. Peters, Vanessa Linke, Katherine A. Overmyer, Austin Z. Salome, Alexander S. Hebert, Catherine E. Vincent, Nicholas W. Kwiecien, Matthew J. P. Rush, Michael S. Westphall, Mark Craven, Nurten A. Akarsu, Robert W. Taylor, Joshua J. Coon, David J. Pagliarini

المساهمون: Acibadem University Dspace

المصدر: Nature

مصطلحات موضوعية: Proteomics, Mitochondrial Diseases, Multidisciplinary, Proteome, Systems Biology, Cell Cycle Proteins, Mass Spectrometry, Article, Mitochondria, Mitochondrial Proteins, Lipidomics, Humans, Metabolomics, Energy Metabolism, Cation Transport Proteins, Transcription Factors, rab5 GTP-Binding Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110ea389757cf2663921890242d13c0bTest
https://doi.org/10.1038/s41586-022-04765-3Test

المؤلفون: McDonald, Thomas V, Yu, Zhihui, Ming, Zhen, Palma, Eugen, Meyers, Marian B, Wang, Ke-Wei, Goldstein, Steve AN, Fishman, Glenn I

المصدر: Nature. 388(6639)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Genetics, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Aetiology, Underpinning research, Animals, CHO Cells, Cation Transport Proteins, Cricetinae, DNA-Binding Proteins, ERG1 Potassium Channel, Electrophysiology, Epitopes, Ether-A-Go-Go Potassium Channels, Hemagglutinins, Humans, Ion Channel Gating, Myocardium, Potassium Channels, Potassium Channels, Voltage-Gated, Protein Binding, Proto-Oncogene Proteins c-myc, Recombinant Fusion Proteins, Trans-Activators, Transcriptional Regulator ERG, Transfection, Xenopus, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4sq7h1bcTest

المؤلفون: Bjørn Panyella Pedersen, David L. Stokes, Ching-Shin Huang

المصدر: Nature
Huang, C-S, Pedersen, B P & Stokes, D 2017, ' Crystal structure of the potassium-importing KdpFABC membrane complex ', Nature, vol. 546, no. 7660, pp. 681-685 . https://doi.org/10.1038/nature22970Test

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein subunit, ATPase, Potassium, chemistry.chemical_element, Crystallography, X-Ray, Article, 03 medical and health sciences, ATP hydrolysis, Escherichia coli, Phosphorylation, Cation Transport Proteins, Adenosine Triphosphatases, Membrane potential, Multidisciplinary, 030102 biochemistry & molecular biology, biology, Escherichia coli Proteins, Membrane Proteins, Potassium channel, Transport protein, Transmembrane domain, 030104 developmental biology, Biochemistry, chemistry, biology.protein, Biophysics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0a80d9a4cbf2f31ee0ce35cc3b69c2Test
https://doi.org/10.1038/nature22970Test

المؤلفون: Clara Correia-Melo, Mohammad Tauqeer Alam, Lucia Herrera-Dominguez, Michael Mülleder, Viridiana Olin-Sandoval, Jakob Vowinckel, David Alejandro Peña Navarro, Stephan Kamrad, Leonor Miller-Fleming, Jason S. L. Yu, Markus Ralser, Robert Haas, Joanna Segal, Oscar Méndez-Lucio

المصدر: Nature

مصطلحات موضوعية: Antioxidant, Saccharomyces cerevisiae Proteins, Organic Cation Transport Proteins, medicine.medical_treatment, Glutamine, Oxidative phosphorylation, Saccharomyces cerevisiae, Pentose phosphate pathway, medicine.disease_cause, Ornithine Decarboxylase, Article, Antioxidants, Antiporters, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cadaverine, medicine, Polyamines, QD, 030304 developmental biology, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, Multidisciplinary, Lysine, QK, Metabolism, Glutathione, Oxidants, QR, chemistry, Biochemistry, Polyamine, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress, NADP

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9896e3af4cdc692a4a69e2012713cf7Test
https://pubmed.ncbi.nlm.nih.gov/31384051Test

المؤلفون: Arthur Laganowsky, Timothy M. Allison, Martin B. Ulmschneider, Andrew Baldwin, Matteo T. Degiacomi, Eamonn Reading, Carol V. Robinson

المصدر: Laganowsky, A, Reading, E, Allison, T M, Ulmschneider, M B, Degiacomi, M T, Baldwin, A J & Robinson, C V 2014, ' Membrane proteins bind lipids selectively to modulate their structure and function ', Nature, vol. 510, pp. 172-175 . https://doi.org/10.1038/nature13419Test
Nature

مصطلحات موضوعية: Models, Molecular, Protein Folding, Mycobacterium tuberculosis/chemistry, Protein Conformation, Lipid Bilayers, Membrane Lipids/chemistry, Ammonia/metabolism, Protein Conformation/drug effects, Aquaporins/chemistry, Crystallography, X-Ray, Ion Channels/chemistry, Protein Folding/drug effects, 01 natural sciences, Ion Channels, Mass Spectrometry, Substrate Specificity, Protein structure, Lipid bilayer, Cation Transport Proteins, Integral membrane protein, 0303 health sciences, Multidisciplinary, Protein Stability, Cation Transport Proteins/chemistry, Chemistry, Escherichia coli Proteins, Peripheral membrane protein, Phosphatidylglycerols, 3. Good health, Transport protein, Biochemistry, lipids (amino acids, peptides, and proteins), Protein folding, Lipid Bilayers/chemistry, Cardiolipins, Escherichia coli/chemistry, Membrane lipids, Protein Unfolding/drug effects, Aquaporins, 010402 general chemistry, Article, Membrane Lipids, 03 medical and health sciences, Bacterial Proteins, Ammonia, Bacterial Proteins/chemistry, Escherichia coli, Protein Stability/drug effects, Protein Unfolding, 030304 developmental biology, Apoproteins/chemistry, Membrane Proteins, Membrane Proteins/chemistry, Cardiolipins/chemistry, Mycobacterium tuberculosis, 0104 chemical sciences, Membrane protein, Escherichia coli Proteins/chemistry, Phosphatidylglycerols/chemistry, Apoproteins

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3128efd03523c7d2fc96b193c4d13773Test
https://doi.org/10.1038/nature13419Test

المؤلفون: Xiaojie Yao, Dennis J. Thiele, Donita C. Brady, Matthew S. Crowe, G. Aaron Hobbs, Stefan Knapp, Apirat Chaikuad, Michelle L. Turski, Kunhong Xiao, Sharon L. Campbell, Christopher M. Counter

المصدر: Nature

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, MAPK/ERK pathway, Indoles, Lung Neoplasms, endocrine system diseases, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase 3, Mitogen-activated protein kinase kinase, Biology, medicine.disease_cause, environment and public health, Article, Mice, Hepatolenticular Degeneration, Cell Line, Tumor, medicine, Animals, Humans, Phosphorylation, Protein kinase A, Cation Transport Proteins, Chelating Agents, Copper Transporter 1, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase Kinases, Sulfonamides, Multidisciplinary, Kinase, Drug Repositioning, Survival Analysis, 3. Good health, Disease Models, Animal, enzymes and coenzymes (carbohydrates), Cell Transformation, Neoplastic, Vemurafenib, Drug Resistance, Neoplasm, Cancer research, Female, Carcinogenesis, Copper, V600E

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcfe458105f9e82e01cb9ba8f23ea2cTest
http://europepmc.org/articles/PMC4138975Test

المؤلفون: Pontus Gourdon, Tina Skjørringe, J. Preben Morth, Xiangyu Liu, Lisbeth Birk Møller, Bjørn Panyella Pedersen, Poul Nissen

المصدر: Gourdon, P, Liu, X-Y, Skjørringe, T, Morth, J P, Møller, L B, Pedersen, B P & Nissen, P 2011, ' Crystal structure of a copper-transporting PIB-type ATPase ', Nature, vol. 475, no. 7354, pp. 59-64 . https://doi.org/10.1038/nature10191Test

مصطلحات موضوعية: Models, Molecular, Cytoplasm, ATP7A, Mutation, Missense, Biology, Crystallography, X-Ray, Legionella pneumophila, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Cell membrane, Structure-Activity Relationship, 03 medical and health sciences, Protein structure, Bacterial Proteins, Hepatolenticular Degeneration, medicine, Humans, Menkes Kinky Hair Syndrome, Cation Transport Proteins, 030304 developmental biology, Adenosine Triphosphatases, 0303 health sciences, Binding Sites, Multidisciplinary, Cell Membrane, 030302 biochemistry & molecular biology, Biological Transport, Protein Structure, Tertiary, Transport protein, Transmembrane domain, medicine.anatomical_structure, Membrane protein, Biochemistry, Copper-Transporting ATPases, Copper-transporting ATPases, Biophysics, Calcium, Copper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e235d4ff3a7e495d400c96b417120eTest
https://doi.org/10.1038/nature10191Test

المؤلفون: Sylvie Lalonde, Dominique Loqué, Loren L. Looger, Wolf B. Frommer, N. von Wirén

المصدر: Nature. 446:195-198

مصطلحات موضوعية: Models, Molecular, Transcriptional Activation, Protein subunit, Allosteric regulation, Arabidopsis, Cytosol, Protein structure, Allosteric Regulation, Cation Transport Proteins, Conserved Sequence, Plant Proteins, Multidisciplinary, Chemistry, C-terminus, Biological Transport, Transporter, Membrane transport, Protein Structure, Tertiary, Quaternary Ammonium Compounds, Protein Subunits, Membrane protein, Biochemistry, Archaeoglobus fulgidus, Multiprotein Complexes, Mutation, Biophysics, Phosphorylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bc165ed975776eed2cdeca92015381Test
https://doi.org/10.1038/nature05579Test

المؤلفون: Elena Dobrovetsky, Rongguang Zhang, Alexey Bochkarev, Andrzej Joachimiak, Vladimir V. Lunin, Galina Khutoreskaya, Aled M. Edwards, Declan A. Doyle, Christopher M. Koth, Michael E. Maguire

المصدر: Nature. 440:833-837

مصطلحات موضوعية: Models, Molecular, Cations, Divalent, Magnesium transporter, Static Electricity, Crystallography, X-Ray, Article, Ion Channels, Protein Structure, Secondary, Protein structure, Bacterial Proteins, Magnesium, Thermotoga maritima, Cation Transport Proteins, Magnesium ion, Ion channel, Multidisciplinary, biology, Chemistry, biology.organism_classification, Transport protein, Transmembrane domain, Structural biology, Biochemistry, Biophysics, Crystallization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d615fe14e4b94293335197047e294bf5Test
https://doi.org/10.1038/nature04642Test