Diaphragmatic dysfunction at the first visit to a chest diseases outpatient clinic in 500 patients with amyotrophic lateral sclerosis
| العنوان: | Diaphragmatic dysfunction at the first visit to a chest diseases outpatient clinic in 500 patients with amyotrophic lateral sclerosis |
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| المؤلفون: | Esen Kiyan, Hacer Durmus, Zuleyha Bingol, Aylin Pihtili, Yesim Parman |
| المصدر: | Muscle & Nerve. 63:683-689 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Vital capacity, Physiology, Diaphragm, Vital Capacity, Diaphragmatic breathing, Polysomnography, 030105 genetics & heredity, Ambulatory Care Facilities, Hypoxemia, Hypercapnia, 03 medical and health sciences, Cellular and Molecular Neuroscience, FEV1/FVC ratio, 0302 clinical medicine, Physiology (medical), Humans, Medicine, Outpatient clinic, Aged, Retrospective Studies, medicine.diagnostic_test, business.industry, Amyotrophic Lateral Sclerosis, Middle Aged, medicine.disease, Respiratory Function Tests, Obstructive sleep apnea, Pulse oximetry, Anesthesia, Female, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | INTRODUCTION In this study, we aimed to evaluate diaphragmatic dysfunction (DD) by using a practical approach in patients with amyotrophic lateral sclerosis (ALS) at the first visit to a chest diseases outpatient clinic. METHODS Patients with ALS seen in our outpatient clinic for the past 5 y and followed up for at least 1 y, were retrospectively evaluated. Having at least one of the following three criteria was accepted as DD: (a) paradoxical abdominal movement (PAM), (b) sitting-supine forced vital capacity (FVC) difference ≥ 20%, (c) sitting-supine arterial oxygen saturation measured by pulse oximetry (SpO2 ) difference ≥ 4%. Respiratory symptoms, arterial blood gas analysis, sleep studies, noninvasive mechanical ventilation use, and mortality were recorded. RESULTS Five-hundred patients with ALS were included (female/male: 220/280, age: 58.9 ± 11.3 y). Of the patients, 22.8% had daytime hypercapnia. DD was observed in 55% of the patients (PAM in 112, sitting-supine FVC difference ≥ 20% in 50, and sitting-supine SpO2 difference ≥ 4% in 113 patients). Of the patients with DD, 31.6% (n = 87) had no respiratory symptoms, 46.4% had FVC > 70% and 33.5% had FVC |
| تدمد: | 1097-4598 0148-639X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cda2c360f31c96a868ac69dfa556585Test https://doi.org/10.1002/mus.27200Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....7cda2c360f31c96a868ac69dfa556585 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10974598 0148639X |
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