التفاصيل البيبلوغرافية
العنوان: |
Myelin imaging measures as predictors of cognitive impairment in MS patients: A hybrid PET-MRI study |
المؤلفون: |
Campanholo, KR, Pitombeira, MS, Rimkus, CM, Mendes, MF, Apóstolos-Pereira, SL, Busatto Filho, G, Callegaro, D, Buchpiguel, CA, Duran, FLS, De Paula Faria, D |
المصدر: |
Multiple Sclerosis and Related Disorders; January 2022, Vol. 57 Issue: 1 |
مستخلص: |
•Different imaging techniques (DTI, MTR and 11C-PIB PET) were compared.•All images from one subject were acquired simultaneously in a PET/MR hybrid system.•Low MTR in thalamus and corpus callosum were predictors of cognitive impairment in the entire MS cohort.•DTI showed association in PMS, while MTR and 11C-PIB uptake (DVR) in RRMS.•11C-PIB PET was a method more consistently associated with cognitive parameters. |
قاعدة البيانات: |
Supplemental Index |