دورية أكاديمية

Atypical propriospinal myoclonus with possible relationship to α interferon therapy ( A videotape accompanies this article.).

التفاصيل البيبلوغرافية
العنوان: Atypical propriospinal myoclonus with possible relationship to α interferon therapy ( A videotape accompanies this article.).
المؤلفون: Isabelle Benatru, Stéphane Thobois, Nathalie Andre-Obadia, Pierre-Marie Gonnaud, Yara Beaugendre, Colette Berger, Michel Gonce, Emmanuel Broussolle
المصدر: Movement Disorders; Dec2003, Vol. 18 Issue 12, p1564-1568, 5p
مستخلص: We report on a man who received interferon-α 2a therapy for kidney cancer and who subsequently developed propriospinal myoclonus. The myoclonus was noted at rest and during movement. The jerks were reinforced by cutaneous stimuli and tendon taps and spread to the spinal cord via polysynaptic propriospinal pathways. Cerebrospinal fluid analysis, spinal cord magnetic resonance imaging, electroencephalogram with back-averaging, and somatosensory-evoked potentials were normal. No antineuronal antibodies were found. Although the mechanism of interferon neurotoxicity remains unclear, the possible responsibility of interferon was considered, as no focal lesion or paraneoplastic pathology were disclosed. © 2003 Movement Disorder Society [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:08853185
DOI:10.1002/mds.10614