Synthesis and characterization of mono- and bicyclic heterocyclic derivatives containing 1,2,4-triazole, 1,3,4-thia-, and -oxadiazole rings
| العنوان: | Synthesis and characterization of mono- and bicyclic heterocyclic derivatives containing 1,2,4-triazole, 1,3,4-thia-, and -oxadiazole rings |
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| المؤلفون: | Wael A. El-Sayed, Hala E. M. Tolan, Mohamed I. Hegab, Adel A.-H. Abdel-Rahman |
| المصدر: | Monatshefte für Chemie - Chemical Monthly. 139:1055-1060 |
| بيانات النشر: | Springer Science and Business Media LLC, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | chemistry.chemical_compound, chemistry, Bicyclic molecule, Stereochemistry, Proton NMR, Oxadiazole, 1,2,4-Triazole, Thio, General Chemistry, Heterocyclic derivatives |
| الوصف: | A series of new N- and S-substituted 1,3,4-oxadiazole derivatives were synthesized. 5-Pyridin-3-yl-3-[2-(5-thioxo-4,5-dihydro-l,3,4-thiadiazol-2-yl)ethyl]-1,3,4-oxadiazole-2(3H)-thione and 5-[(5-(pyridin-3-yl)-1,3,4-oxadiazol-2-ylthio)methyl]-N-phenyl-1,3,4-thiadiazol-2-amine were formed by cyclization of 3-(5-pyridin-3-yl-2-thioxo-1,3,4-oxadiazol-3(2H)-ylpropanimidohydrazide and 2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)thio]thiosemicarbazide with CS2 and H2SO4. On the other hand, a number of new bicyclic 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole derivatives were synthesized. 6-Pyridin-3-ylbis[1,2,4]‐triazolo[3,4-b:4′,3′-d][1,3,4]thiadiazole-3(2H)-thione was synthesized by reaction of 6-(hydrazino)-3-pyridine-3-yl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole with CS2/KOH/EtOH. The structures of the newly synthesized compounds were elucidated by the spectral and analytical data IR, Mass, and 1H NMR spectra. |
| تدمد: | 1434-4475 0026-9247 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::658717655a87b40968468ec169251b43Test https://doi.org/10.1007/s00706-008-0881-9Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........658717655a87b40968468ec169251b43 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14344475 00269247 |
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