Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR

التفاصيل البيبلوغرافية
العنوان:	Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR
المؤلفون:	Lihe Zhang, Liangren Zhang, Min Dong, Jian Liu, Kehui Zhang, Zhenjun Yang, Xiangchen Huang
المصدر:	Molecules, Vol 15, Iss 12, Pp 8689-8701 (2010)
بيانات النشر:	MDPI AG, 2010.
سنة النشر:	2010
المجموعة:	LCC:Organic chemistry
مصطلحات موضوعية:	cADPR analogue, acyclic cADPR analogue, trifluoromethylation, synthesis, Organic chemistry, QD241-441
الوصف:	A novel trifluoromethylated analogue of cADPR, 8-CF3-cIDPDE (5) was designed and synthesized via construction of N1,N9-disubstituted hypoxanthine, trifluoromethylation and intramolecular condensation. A series of acyclic analogues of cADPR were also designed and synthesized. These compounds could be useful molecules for studying the structure-activity relationship of cADPR analogues and exploring the cADPR/RyR Ca2+ signalling system.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1420-3049
العلاقة:	http://www.mdpi.com/1420-3049/15/12/8689Test/; https://doaj.org/toc/1420-3049Test
DOI:	10.3390/molecules15128689
الوصول الحر:	https://doaj.org/article/5562f9da30a1451fad0e478af1e2063fTest
رقم الانضمام:	edsdoj.5562f9da30a1451fad0e478af1e2063f
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	14203049
DOI:	10.3390/molecules15128689