نتائج البحث - "Non-Receptor Type 1"

1

Water Extract of Mungbean (Vigna radiata L.) Inhibits Protein Tyrosine Phosphatase-1B in Insulin-Resistant HepG2 Cells

المؤلفون: Parichat Hongsprabhas, Angsuma Phongphisutthinan, Orathai Saeting, Kasemsiri Chandarajoti, Sudathip Sae-tan

المصدر: Molecules
Volume 26
Issue 5
Molecules, Vol 26, Iss 1452, p 1452 (2021)

مصطلحات موضوعية: Glycation End Products, Advanced, mungbean, 030309 nutrition & dietetics, Glucose uptake, medicine.medical_treatment, Pharmaceutical Science, FOXO1, Protein tyrosine phosphatase, Analytical Chemistry, GSK-3, Drug Discovery, Insulin, Enzyme Inhibitors, Protein Tyrosine Phosphatase, Non-Receptor Type 1, 0303 health sciences, biology, diabetes, Chemistry, Temperature, 04 agricultural and veterinary sciences, Hep G2 Cells, 040401 food science, Biochemistry, Chemistry (miscellaneous), protein tyrosine phosphatase-1B, Molecular Medicine, Phosphoenolpyruvate carboxykinase, Carbohydrate metabolism, Article, lcsh:QD241-441, 03 medical and health sciences, 0404 agricultural biotechnology, lcsh:Organic chemistry, Phenols, medicine, Humans, Glycoside Hydrolase Inhibitors, Physical and Theoretical Chemistry, Flavonoids, Plant Extracts, Vigna, Organic Chemistry, Water, glucose uptake, Insulin receptor, Glucose, Gene Expression Regulation, biology.protein, alpha-Amylases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fcd1e256eac534d89af27bc0d3adfeTest

2

In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B

المؤلفون: Roberta Moschini, Ilaria Nesi, Trung Ngoc Nguyen, Antonella Del Corso, Rosanna Maccari, Massimo Genovese, Paolo De Paoli, Ilenia Adornato, Gerhard Wolber, Rosaria Ottanà, Mario Cappiello, Alexandra Naß

المصدر: Molecules
Volume 26
Issue 2
Molecules, Vol 26, Iss 330, p 330 (2021)

مصطلحات موضوعية: 4-thiazolidinones, Drug Evaluation, Preclinical, Pharmaceutical Science, Disease, Pharmacology, Ligands, Analytical Chemistry, Mice, 0302 clinical medicine, Drug Discovery, Enzyme Inhibitors, Non-Receptor Type 1, Aldehyde Reductase, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, 0303 health sciences, Chemistry, Hep G2 Cells, aldose reductase, Preclinical, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, diabetes mellitus, Molecular Medicine, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik, C2C12, Aldose reductase, Diabetes mellitus, Molecular docking, Multi-target ligands, Protein tyrosine phosphatase 1B, Animals, Diabetes Mellitus, Humans, Structure-Activity Relationship, Hypoglycemic Agents, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten, multi-target ligands, Article, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, medicine, Structure–activity relationship, Physical and Theoretical Chemistry, 030304 developmental biology, Organic Chemistry, molecular docking, medicine.disease, Enzyme, Cell culture, Drug Evaluation, Protein Tyrosine Phosphatase, protein tyrosine phosphatase 1B

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc68d1010cf1de2f7cbda56990a5249Test
https://doi.org/10.3390/molecules26020330Test

3

PTP1B Inhibitory Secondary Metabolites from an Antarctic Fungal Strain Acremonium sp. SF-7394

المؤلفون: Hye Jin Kim, Dongho Lee, Tai Kyoung Kim, Dong-Cheol Kim, Joung Han Yim, Xiao-Jun Li, Jae Hak Sohn, Youn-Chul Kim, Haeun Kwon, Hyuncheol Oh

المصدر: Molecules, Vol 26, Iss 5505, p 5505 (2021)
Molecules
Volume 26
Issue 18

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7471898b26d439d92930f02ee6e896eeTest
https://doi.org/10.3390/molecules26185505Test

4

On the Inhibitability of Natural Products Isolated from Tetradium ruticarpum towards Tyrosine Phosphatase 1B (PTP1B) and α-Glucosidase (3W37): An In Vitro and In Silico Study

المؤلفون: Dao-Cuong To, Nguyen Thi Ai Nhung, Tien-Dung Nguyen, Huu-Tho Nguyen, Phan Tu Quy, Phi Hung Nguyen, Thi-Thuy Do, Thanh Q. Bui, Truong-Nhan Ngu, The-Hung Nguyen, Manh-Hung Tran, Quoc-Toan Tran, Phan-Phuoc Hien

المصدر: Molecules
Volume 26
Issue 12
Molecules, Vol 26, Iss 3691, p 3691 (2021)

مصطلحات موضوعية: food.ingredient, α-glucosidase (3W37), In silico, Pharmaceutical Science, Tetradium ruticarpum, Protein tyrosine phosphatase, 010402 general chemistry, tyrosine phosphatase 1B (PTP1B), 01 natural sciences, Molecular Docking Simulation, Article, Evodia, Analytical Chemistry, Structure-Activity Relationship, QD241-441, food, Drug Discovery, Glycoside Hydrolase Inhibitors, Enzyme Inhibitors, Physical and Theoretical Chemistry, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Biological Products, Plant Extracts, 010405 organic chemistry, Organic Chemistry, alpha-Glucosidases, In vitro, 0104 chemical sciences, Amino acid, Enzyme, Biochemistry, chemistry, Chemistry (miscellaneous), Docking (molecular), Molecular Medicine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1516600473726e26e9fa916f0131c1Test
https://doi.org/10.3390/molecules26123691Test

5

Study on a Fermented Whole Wheat: Phenolic Content, Activity on PTP1B Enzyme and In Vitro Prebiotic Properties

المؤلفون: Monica Di Paola, Diana Di Gioia, Diletta Balli, Giuseppe Pieraccini, Nadia Mulinacci, Marzia Innocenti, Paolo De Paoli, Carlotta De Filippo, Maria Bellumori

المساهمون: Balli D., Bellumori M., Paoli P., Pieraccini G., Di Paola M., De Filippo C., Di Gioia D., Mulinacci N., Innocenti M.

المصدر: Molecules
Volume 24
Issue 6
Molecules (Basel, Online) 24 (2019). doi:10.3390/molecules24061120
info:cnr-pdr/source/autori:Balli, Diletta; Bellumori, Maria; Paoli, Paolo; Pieraccini, Giuseppe; Di Paola, Monica; De Filippo, Carlotta; Di Gioia, Diana; Mulinacci, Nadia; Innocenti, Marzia/titolo:Study on a Fermented Whole Wheat: Phenolic Content, Activity on PTP1B Enzyme and In Vitro Prebiotic Properties/doi:10.3390%2Fmolecules24061120/rivista:Molecules (Basel, Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:24
Molecules, Vol 24, Iss 6, p 1120 (2019)

مصطلحات موضوعية: cereal, medicine.medical_treatment, Pharmaceutical Science, Prebiotic, 01 natural sciences, Analytical Chemistry, Ingredient, chemistry.chemical_compound, Lactobacillus, RNA, Ribosomal, 16S, Drug Discovery, Food science, Chromatography, High Pressure Liquid, Triticum, 2. Zero hunger, Protein Tyrosine Phosphatase, Non-Receptor Type 1, biology, Chemistry, food and beverages, 04 agricultural and veterinary sciences, 040401 food science, Lactobacillus reuteri, Chemistry (miscellaneous), Molecular Medicine, Pediococcus, Fermented Foods, Human, Article, lcsh:QD241-441, Hydrolysis, Metagenomic, 0404 agricultural biotechnology, lcsh:Organic chemistry, Phenols, medicine, Humans, Physical and Theoretical Chemistry, Cereal, Methyl ferulate, Schaftoside, Enzyme Activation, Food Microbiology, Metagenome, Metagenomics, Prebiotics, schaftoside, methyl ferulate, Phenol, 010401 analytical chemistry, Organic Chemistry, Fermented Foods and Beverage, biology.organism_classification, 0104 chemical sciences, Fermentation

وصف الملف: application/pdf; ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcbadcd64cd56370ae8453dd52bcfb0Test

6

Polyphenols from Acorn Leaves (Quercus liaotungensis) Protect Pancreatic Beta Cells and Their Inhibitory Activity against α-Glucosidase and Protein Tyrosine Phosphatase 1B

المؤلفون: Yuanyuan Sun, Jing Xu, Yuqing Zhao, Jiayin Yue, Xude Wang, Xiaoshu Zhang

المصدر: Molecules, Vol 23, Iss 9, p 2167 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 9

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Phytochemicals, Pharmaceutical Science, Acorn, Antioxidants, Analytical Chemistry, Quercus, chemistry.chemical_compound, Insulin-Secreting Cells, Drug Discovery, pancreatic protection, Enzyme Inhibitors, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Molecular Structure, biology, 04 agricultural and veterinary sciences, 040401 food science, Biochemistry, Phytochemical, Chemistry (miscellaneous), Catalase, Molecular Medicine, α-glucosidase and PTP1B inhibitory activities, MIN6, Signal Transduction, Cell Survival, NF-E2-Related Factor 2, Article, Superoxide dismutase, lcsh:QD241-441, 0404 agricultural biotechnology, Functional food, lcsh:Organic chemistry, Humans, Glycoside Hydrolase Inhibitors, Physical and Theoretical Chemistry, Reactive oxygen species, Plant Extracts, Organic Chemistry, Polyphenols, alpha-Glucosidases, Hydrogen Peroxide, Glutathione, acorn leaves, Plant Leaves, Oxidative Stress, polyphenol, chemistry, Polyphenol, biology.protein, Reactive Oxygen Species, Heme Oxygenase-1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9267a59bf56200004200df7a8e61543Test
http://www.mdpi.com/1420-3049/23/9/2167Test

7

High-Resolution Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Vietnamese Plants

المؤلفون: Binh T.D. Trinh, Dan Staerk, Anna K. Jäger

المصدر: Molecules, Vol 22, Iss 7, p 1228 (2017)
Trinh, T D B, Jäger, A K & Stærk, D 2017, ' High-resolution inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Vietnamese plants ', Molecules, vol. 22, no. 7, 1228 . https://doi.org/10.3390/molecules22071228Test
Molecules; Volume 22; Issue 7; Pages: 1228
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

مصطلحات موضوعية: Ficus racemosa, Magnetic Resonance Spectroscopy, medicine.medical_treatment, Pharmaceutical Science, Type 2 diabetes, Pharmacology, 01 natural sciences, Article, type 2 diabetes, PTP1B, Vietnamese medicinal plants, isoflavonoids, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, Insulin resistance, lcsh:Organic chemistry, Drug Discovery, medicine, Humans, Physical and Theoretical Chemistry, IC50, Chromatography, High Pressure Liquid, Flavonoids, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Plants, Medicinal, biology, Plant Extracts, 010405 organic chemistry, Insulin, Organic Chemistry, Ficus, Alpinumisoflavone, medicine.disease, Isoflavones, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Insulin receptor, Diabetes Mellitus, Type 2, chemistry, Chemistry (miscellaneous), biology.protein, Molecular Medicine, Signal transduction, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00d394a1291bc85334a01ff212916a4Test
https://www.mdpi.com/1420-3049/22/7/1228Test

8

Potential of Icariin Metabolites from Epimedium koreanum Nakai as Antidiabetic Therapeutic Agents

المؤلفون: Hyun Ah Jung, Jae Sue Choi, Da Hye Kim, Hee Sook Sohn, Jinwoong Kim

المصدر: Molecules, Vol 22, Iss 6, p 986 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 6; Pages: 986

مصطلحات موضوعية: 0301 basic medicine, Epimedium koreanum Nakai, icariin metabolite, PTP1B, α-glucosidase, molecular docking simulation, Epimedium koreanum, Allosteric regulation, Flavonoid, Pharmaceutical Science, Pharmacology, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, lcsh:Organic chemistry, Drug Discovery, Hypoglycemic Agents, Glycoside Hydrolase Inhibitors, Enzyme kinetics, Enzyme Inhibitors, Physical and Theoretical Chemistry, IC50, Epimedium, Flavonoids, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Plant Extracts, Chemistry, Organic Chemistry, alpha-Glucosidases, Ligand (biochemistry), Protein Tyrosine Phosphatase 1B, Molecular Docking Simulation, 030104 developmental biology, Diabetes Mellitus, Type 2, Biochemistry, Chemistry (miscellaneous), Molecular Medicine, Icariin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffe181d88ada23ec2850d9493328336Test
http://www.mdpi.com/1420-3049/22/6/986Test

9

Design, Synthesis and Biological Evaluation of Stilbene Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B

المؤلفون: Yinghua Ge, Hong Dai, Cui Song, Jia Jin, Yujun Shi, Fei Ye, He Haibing

المصدر: Molecules, Vol 21, Iss 12, p 1722 (2016)
Molecules; Volume 21; Issue 12; Pages: 1722
Molecules

مصطلحات موضوعية: 0301 basic medicine, Lithocholic acid, Stereochemistry, Proton Magnetic Resonance Spectroscopy, Pharmaceutical Science, Article, Mass Spectrometry, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, lcsh:Organic chemistry, Drug Discovery, Stilbenes, Moiety, Physical and Theoretical Chemistry, Isoxazole, Enzyme Inhibitors, IC50, chemistry.chemical_classification, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Molecular Structure, Organic Chemistry, protein tyrosine phosphatase 1B (PTP1B), lithocholic acid, stilbene, inhibitor, Isoxazoles, Combinatorial chemistry, Protein Tyrosine Phosphatase 1B, 030104 developmental biology, Enzyme, chemistry, Chemistry (miscellaneous), Drug Design, Molecular Medicine, Selectivity, Lead compound, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa564b0c368a3a913953c41e1e92edd3Test
http://www.mdpi.com/1420-3049/21/12/1722Test

10

Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B

المؤلفون: Hyun Ah Jung, Yousof Ali, Jae Sue Choi

المصدر: Molecules, Vol 22, Iss 1, p 28 (2016)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 1; Pages: 28

مصطلحات موضوعية: 0301 basic medicine, Pharmaceutical Science, Protein tyrosine phosphatase, Cassia obtusifolia, PTP1B, α-glucosidase, anthraquinones, insulin resistance, alaternin, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Cassia, Catalytic Domain, Drug Discovery, Glycosides, Medicine, Chinese Traditional, chemistry.chemical_classification, Protein Tyrosine Phosphatase, Non-Receptor Type 1, biology, Chemistry, Hep G2 Cells, Molecular Docking Simulation, Biochemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists, Emodin, Stereochemistry, Naphthalenes, Article, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, Cell Line, Tumor, Anthraquinones, Humans, Hypoglycemic Agents, Glycoside Hydrolase Inhibitors, Physical and Theoretical Chemistry, Organic Chemistry, Active site, Glycoside, alpha-Glucosidases, biology.organism_classification, 030104 developmental biology, Enzyme, Glucose, Docking (molecular), biology.protein, Plant Preparations

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4df32eefde0c1dedc2d79a88ba03ba1Test
http://www.mdpi.com/1420-3049/22Test/1/28

تنقيح النتائج