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المؤلفون: Gerald L. Murray, Célia Fontana, Jun Liu, Hugo Varet, Ben Adler, Ruben Halifa, Mathieu Picardeau, David R. Hendrixson, Shuaiqi Guo, Alejandro Buschiazzo, Jean Yves Coppée, Lenka Fule, Odile Sismeiro, Rachel Legendre
المساهمون: Biologie des Spirochètes / Biology of Spirochetes, Institut Pasteur [Paris], Integrative Microbiology of Zoonotic Agents [Paris and Montevideo] (IMiZA), Institut Pasteur de Montevideo, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur [Paris], Université de Paris (UP), Boehringer Ingelheim Pharma GmbH & Co. KG, Pôle Biomics (C2RT), Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris]-Institut Pasteur [Paris], Transcriptome et Epigénome (PF2), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Monash University [Clayton], University of Texas Southwestern Medical Center, Réseau International des Instituts Pasteur (RIIP), Yale University School of Medicine, This research was supported by ANR LEPTOMOVE (18-CE15-0027-01) and the Pasteur International Unit « Integrative Microbiology of Zoonotic Agents » (IMiZA) to MP, NIH R01AI065539 to DRH, and NIAID R01AI087946 to JL. This work is part of the PhD of Lenka Fule., We thank Olivier Gorgette (UBI platform, Institut Pasteur, Paris, France) and Ariel Mechaly (Plateforme de Cristallographie, Institut Pasteur, Paris, France) for help in electron microscopy and protein structure analysis, respectively. We thank Christophe Becavin for RNA-seq analysis, Sébastien Le Hu Nghia for genetic studies and Meng Shao and Qin Gong for their assistance in cryo-ET sample preparation and segmentation. We also thank David Šmajs for the gift of Borrelia DNA, ANR-18-CE15-0027,LEPTOMOVE,Mécanismes moléculaires de la motilité chez les spirochètes: le modèle de l'endoflagelle des leptospires(2018), Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur [Paris] (IP), Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Institut Pasteur [Paris] (IP), Institut Pasteur [Paris] (IP), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Yale School of Medicine [New Haven, Connecticut] (YSM)
المصدر: Molecular Microbiology
Molecular Microbiology, Wiley, 2021, ⟨10.1111/mmi.14831⟩
Molecular Microbiology, 2021, ⟨10.1111/mmi.14831⟩مصطلحات موضوعية: endoflagellum, [SDV]Life Sciences [q-bio], Mutant, Virulence, Flagellum, Microbiology, 03 medical and health sciences, Bacterial Proteins, Leptospira, Humans, Leptospirosis, spirochetes, Molecular Biology, Pathogen, Monomeric GTP-Binding Proteins, 030304 developmental biology, 0303 health sciences, biology, 030306 microbiology, Gene Expression Profiling, Cryoelectron Microscopy, Genetic Complementation Test, Gene Expression Regulation, Bacterial, Periplasmic space, biology.organism_classification, Complementation, motility, Flagella, Spirochaetales, Mutation, FlhG, Bacteria
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56e46e906f99042eae27420f33956dfTest
https://doi.org/10.1111/mmi.14831Test -
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المؤلفون: Jing-Ren Zhang, Xun Lan, Haiteng Deng, Jiao Hu, Wenhao Zhang, Chengwang Zhang, Jing Li, Haoran An
المصدر: Molecular Microbiology. 116:438-458
مصطلحات موضوعية: Transcription, Genetic, Mutant, medicine.disease_cause, Microbiology, Pneumococcal Infections, Virus, Mice, 03 medical and health sciences, chemistry.chemical_compound, Methionine, Bacterial Proteins, Nasopharynx, Streptococcus pneumoniae, medicine, Transcriptional regulation, Animals, Methionine synthase, Molecular Biology, Gene, 030304 developmental biology, 0303 health sciences, biology, 030306 microbiology, medicine.disease, DNA-Binding Proteins, chemistry, Trans-Activators, biology.protein, Female, Meningitis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04b7081fb9d1938e05aa9235ca527baTest
https://doi.org/10.1111/mmi.14724Test -
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المؤلفون: Yumi Iwadate, Yekaterina A. Golubeva, Rouhallah Ramezanifard, Luke A. Fenlon, James M. Slauch
المصدر: Molecular Microbiology. 115:1379-1394
مصطلحات موضوعية: Salmonella typhimurium, Amino Acid Transport Systems, Spermidine, Mutant, Spermine, Biology, Microbiology, Antiporters, 03 medical and health sciences, chemistry.chemical_compound, Cadaverine, Escherichia coli, Putrescine, Inner membrane, Molecular Biology, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Escherichia coli Proteins, Membrane Proteins, Biological Transport, chemistry, Biochemistry, Polyamine, Intracellular
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd188dde296ad0e3ff5ec002d7fff4d2Test
https://doi.org/10.1111/mmi.14686Test -
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المؤلفون: Kevin E. Bruce, Atsushi Taguchi, Michael S. VanNieuwenhze, Michael J. Boersma, Malcolm E. Winkler, Ho-Ching Tiffany Tsui, Melissa M. Lamanna, Erin E. Carlson, Sidney L. Shaw, Amilcar J. Perez
المصدر: Mol Microbiol
مصطلحات موضوعية: Cell division, Mutant, Cell Cycle Proteins, Peptidoglycan, Biology, medicine.disease_cause, Ring (chemistry), Microbiology, Article, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Streptococcus pneumoniae, medicine, Penicillin-Binding Proteins, FtsZ, Molecular Biology, Fluorescent Dyes, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Peptidoglycan synthesis, Aminoacyltransferases, biology.organism_classification, Cell biology, chemistry, Peptidyl Transferases, biology.protein, NODAL, Cell Division, Bacteria
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449e62c343353c1668c61f3559c5ed3dTest
https://doi.org/10.1111/mmi.14659Test -
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المؤلفون: Yu-Wen Huang, Chih-Yen King, Vitaly V. Kushnirov
المصدر: Molecular Microbiology. 115:774-788
مصطلحات موضوعية: Genetics, Protein Folding, 0303 health sciences, Saccharomyces cerevisiae Proteins, biology, Prions, 030306 microbiology, Mutant, Prion strain, Saccharomyces cerevisiae, Microbiology, Yeast, 03 medical and health sciences, Chaperone (protein), biology.protein, Chaperone activity, Molecular Biology, Heat-Shock Proteins, Molecular Chaperones, Peptide Termination Factors, Sequence Deletion, 030304 developmental biology, Thermostability
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a909a3b3bad6718b78bc057c47bad038Test
https://doi.org/10.1111/mmi.14643Test -
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المؤلفون: Kirsten Jung, Luciano M Prosa, M. Karina Herrera Seitz, Claudia A. Studdert, Rocío S Balmaceda, Ana Gasperotti
المصدر: Molecular Microbiology. 115:672-683
مصطلحات موضوعية: DNA, Bacterial, Chemoreceptor, Stereochemistry, High-throughput screening, Mutant, Carboxylic Acids, Ligands, Benzoates, Microbiology, 03 medical and health sciences, Bacterial Proteins, Protein Domains, Escherichia coli, Hydroxybenzoates, Seawater, Halomonas titanicae, Receptor, Molecular Biology, 030304 developmental biology, Dicarboxylic Acid Transporters, 0303 health sciences, Halomonas, Chemotactic Factors, biology, 030306 microbiology, Chemotaxis, biology.organism_classification, Chemoreceptor Cells, High-Throughput Screening Assays, Direct binding, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189ff4780b82b6255f1e79f6c359c3dbTest
https://doi.org/10.1111/mmi.14630Test -
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المؤلفون: Dimitar Plamenov Petrov, Bruno Pinheiro, Lingyun Guo, Marc Bramkamp, Gustavo Benevides Martins, Kirsten Jung
المصدر: Molecular Microbiology. 115:320-331
مصطلحات موضوعية: 0303 health sciences, 030306 microbiology, Permease, Mutant, Glucose transporter, PEP group translocation, Biology, Microbiology, Corynebacterium glutamicum, 03 medical and health sciences, Biochemistry, Elongation factor P, Phosphoenolpyruvate carboxykinase, Molecular Biology, 030304 developmental biology, Polyproline helix
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cc32e7e5bfb2729ab6aadbcc5b249da4Test
https://doi.org/10.1111/mmi.14618Test -
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المؤلفون: Swaine L. Chen, Wee Boon Tan, Shu-Sin Chng, Xue Li Guan, Rahul Shrivastava, Xiang'Er Jiang, Deborah Chwee San Seow
المصدر: Molecular Microbiology. 114:991-1005
مصطلحات موضوعية: Cell Membrane Permeability, Mutant, Biology, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Cell Wall, Escherichia coli, Homeostasis, Molecular Biology, Barrier function, 030304 developmental biology, Diacylglycerol kinase, Antigens, Bacterial, 0303 health sciences, 030306 microbiology, Escherichia coli Proteins, Phenotype, Cell biology, Bacterial Outer Membrane, chemistry, Mutation, Peptidoglycan, Periplasmic Proteins, Cell envelope, Bacterial outer membrane, Biogenesis, Bacterial Outer Membrane Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489387f194b02f630825244a3220060cTest
https://doi.org/10.1111/mmi.14590Test -
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المؤلفون: Assaf Raz, Justin Merritt, Jens Kreth, Hua Qin, Vincent A. Fischetti, Zhoujie Xie, Zhengzhong Zou, Shan Zhang
المصدر: Mol Microbiol
مصطلحات موضوعية: Operon, Mutant, Endogeny, Biology, Microbiology, Article, Streptococcus mutans, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Bacteriocins, Transcription (biology), Molecular Biology, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Membrane Proteins, Gene Expression Regulation, Bacterial, Cell biology, Membrane protein, chemistry, Signal transduction, Function (biology), DNA, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a411198a04b837aacf24489b5fa825Test
https://doi.org/10.1111/mmi.14576Test -
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المؤلفون: William Margolin, Steven L. Distelhorst, Bo Hu, Kara M. Schoenemann, Marcin Krupka, Veronica W. Rowlett
المصدر: Molecular Microbiology. 109:676-693
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Cell division, 030106 microbiology, Mutant, Cell Cycle Proteins, macromolecular substances, Biology, medicine.disease_cause, Microbiology, Article, Protein filament, 03 medical and health sciences, Adenosine Triphosphate, Bacterial Proteins, Escherichia coli, medicine, FtsZ, Molecular Biology, Cytoskeleton, Cytokinesis, Escherichia coli Proteins, fungi, Lipids, Cytoskeletal Proteins, Cytoplasm, Gain of Function Mutation, Biophysics, biology.protein, bacteria, Mutant Proteins, FtsA, Cell Division
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b698ac4cf551d2991910f6f79d87c965Test
https://doi.org/10.1111/mmi.14069Test