التفاصيل البيبلوغرافية
| العنوان: |
Proteomic changes induced by histone demethylase JMJD3 in TNF alpha-treated human monocytic (THP-1) cells. |
| المؤلفون: |
Das, Amitabh1 amitabhdas.kn@gmail.com, Das, Nando Dulal1 nando.hu@gmail.com, Jung, Kyoung Hwa1 khjung2@gmail.com, Park, Ji Hyun1 b88424@gmail.com, Lee, Hyung Tae1 photod@naver.com, Han, DalMuri1 holystom@gmail.com, Choi, Mi Ran1 miran_choi@hotmail.com, Kang, Sung Chul1 gujiju11@gmail.com, Chai, Young Gyu1 ygchai@hanyang.ac.kr |
| المصدر: |
Molecular Immunology. Nov2013, Vol. 56 Issue 1/2, p113-122. 10p. |
| مصطلحات موضوعية: |
*PROTEOMICS, *HISTONE demethylases, *TUMOR necrosis factors, *MONOCYTIC leukemia, *CANCER cells, *BIOMARKERS, *GENETIC regulation, *CELLULAR signal transduction |
| مستخلص: |
Highlights: [•] We identify proteomic biomarkers in JMJD3-attenuated THP-1 cells. [•] Establish the IPA based functional proteomics in JMJD3-attenuated THP-1 cells. [•] Suppress key inflammatory regulators such as TRIM5, GPx, GMFG in JMJD3-kd cells. [•] Find JMJD3-based molecular targets and crucial pathways in inflammatory signaling. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
