Ecology drives the evolution of diverse social strategies in Pseudomonas aeruginosa
| العنوان: | Ecology drives the evolution of diverse social strategies in Pseudomonas aeruginosa |
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| المؤلفون: | Figueiredo, Alexandre R T, Wagner, Andreas, Kümmerli, Rolf |
| المساهمون: | University of Zurich, Figueiredo, Alexandre R T |
| المصدر: | Molecular Ecology |
| مصطلحات موضوعية: | 0106 biological sciences, Evolution, Iron, Cheating, Siderophores, Genomics, Biology, medicine.disease_cause, 010603 evolutionary biology, 01 natural sciences, UFSP13-7 Evolution in Action: From Genomes to Ecosystems, 10127 Institute of Evolutionary Biology and Environmental Studies, 03 medical and health sciences, chemistry.chemical_compound, 1311 Genetics, Behavior and Systematics, Genetics, medicine, Humans, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, Experimental evolution, Pyoverdine, Ecology, Pseudomonas aeruginosa, fungi, Quorum Sensing, Quorum sensing, 1105 Ecology, Evolution, Behavior and Systematics, chemistry, Trait, 570 Life sciences, biology, 590 Animals (Zoology), Social evolution, 11493 Department of Quantitative Biomedicine |
| الوصف: | Bacteria often cooperate by secreting molecules that can be shared as public goods between cells. Because the production of public goods is subject to cheating by mutants that exploit the good without contributing to it, there has been great interest in elucidating the evolutionary forces that maintain cooperation. However, little is known about how bacterial cooperation evolves under conditions where cheating is unlikely to be of importance. Here we use experimental evolution to follow changes in the production of a model public good, the iron-scavenging siderophore pyoverdine, of the bacterium Pseudomonas aeruginosa. After 1200 generations of evolution in nine different environments, we observed that cheaters only reached high frequency in liquid medium with low iron availability. Conversely, when adding iron to reduce the cost of producing pyoverdine, we observed selection for pyoverdine hyperproducers. Similarly, hyperproducers also spread in populations evolved in highly viscous media, where relatedness between interacting individuals is increased. Whole-genome sequencing of evolved clones revealed that hyperproduction is associated with mutations involving genes encoding quorum-sensing communication systems, while cheater clones had mutations in the iron-starvation sigma factor or in pyoverdine biosynthesis genes. Our findings demonstrate that bacterial social traits can evolve rapidly in divergent directions, with particularly strong selection for increased levels of cooperation occurring in environments where individual dispersal is reduced, as predicted by social evolution theory. Moreover, we establish a regulatory link between pyoverdine production and quorum-sensing, showing that increased cooperation with respect to one trait (pyoverdine) can be associated with the loss (quorum-sensing) of another social trait. |
| وصف الملف: | Molecular_Ecology_-_2021_-_Figueiredo_-_Ecology_drives_the_evolution_of_diverse_social_strategies_in_Pseudomonas_aeruginosa.pdf - application/pdf; Figueiredo_etal_MS_Final.pdf - application/pdf |
| اللغة: | English |
| تدمد: | 1365-294X 0962-1083 |
| DOI: | 10.1111/mec.16119 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f0faa875cffa44dda7a265068a83f8Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e9f0faa875cffa44dda7a265068a83f8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1365294X 09621083 |
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| DOI: | 10.1111/mec.16119 |