دورية أكاديمية
Mitophagy, metabolism, and cell fate
| العنوان: | Mitophagy, metabolism, and cell fate |
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| المؤلفون: | Lorena Esteban-Martínez, Elena Sierra-Filardi, Patricia Boya |
| المصدر: | Molecular & Cellular Oncology, Vol 4, Iss 5 (2017) |
| بيانات النشر: | Taylor & Francis Group, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | autophagy, metabolic reprogramming, hypoxia, bnip3l, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Mitophagy is the process by which cells eliminate damaged or superfluous mitochondria by degrading them within lysosomes. We show that during development, selective removal of mitochondria by autophagy induces a metabolic shift toward glycolysis that is essential for differentiation of several cell types. These findings suggest potential applications of cell-fate manipulation strategies targeting mitophagy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2372-3556 23723556 |
| العلاقة: | https://doaj.org/toc/2372-3556Test |
| DOI: | 10.1080/23723556.2017.1353854 |
| الوصول الحر: | https://doaj.org/article/a674a358edb541e2aa3239b3cface1d3Test |
| رقم الانضمام: | edsdoj.674a358edb541e2aa3239b3cface1d3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23723556 |
|---|---|
| DOI: | 10.1080/23723556.2017.1353854 |