Microbiome analysis reveals gut microbiota alteration of early-weaned Yimeng black goats with the effect of milk replacer and age
| العنوان: | Microbiome analysis reveals gut microbiota alteration of early-weaned Yimeng black goats with the effect of milk replacer and age |
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| المؤلفون: | Aoyun Li, Yongzhu Li, Zhaoqing Han, Yan Yang, Taihua Jin, Shenjin Lv, Songkang Qin, Kun Li |
| المصدر: | Microbial Cell Factories Microbial Cell Factories, Vol 20, Iss 1, Pp 1-14 (2021) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | China, Yimeng black goats, Milk replacer, Propionibacterium, lcsh:QR1-502, Bioengineering, Weaning, Gut microbiota, Weaned, Gut flora, medicine.disease_cause, digestive system, Applied Microbiology and Biotechnology, lcsh:Microbiology, Feces, 03 medical and health sciences, Age, RNA, Ribosomal, 16S, medicine, Animals, Eubacterium, Microbiome, Food science, 030304 developmental biology, 0303 health sciences, Bacteria, biology, 030306 microbiology, Goats, Research, Ruminococcus, Lachnospiraceae, Pathogenic bacteria, biology.organism_classification, Animal Feed, Gastrointestinal Microbiome, Milk, Animals, Newborn, Milk Substitutes, Biotechnology, Ruminococcaceae |
| الوصف: | Background Colonization of intestinal microbiota in ruminant during the early life is important to host health, metabolism and immunity. Accumulating evidence revealed the ameliorative effect of milk replacer administration in the gut microbial development of early-weaned ruminants. Yimeng black goats (YBGs) inhabiting Shandong, China show a complex intestinal microbial ecosystem, but studies of their gut microbiota are still insufficient to report. Here, this study was performed to investigate how the gut microbiota develops in weaned YBGs with the effect of age and milk replacer. Results Results indicated that both age and milk replacer were important factors to change the gut microbiota of YBGs. Although the alpha diversity of gut microbiota did not change with the age of YBGs, the taxonomic compositions significantly changed. The relative abundance of some beneficial bacteria such as Lachnospiraceae, Ruminococcaceae, Ruminiclostridium, Eubacterium and Barnesiella significantly decreased and subsequently increase with age, which contributes to maintain the stability of intestinal environment and realize the diversity of intestinal functions. The relative abundance of Porphyromonas, Brevundimonas, Flavobacterium, Stenotrophomonas, Propionibacterium, Acinetobacter, Enterococcus and Clostridium belong to pathogenic bacteria in milk replacer-treated YBGs was significantly decreased. Additionally, some beneficial bacteria such as Ruminococcus, Ruminococcaceae, Christensenellaceae and Ruminiclostridium also display a trend of decreasing first followed by gradually increasing. Conclusions This study first revealed the gut bacterial community alterations in YBGs with the effect of age and milk replacer. This study also characterized the gut microbial distribution in YBGs with different ages and provided better insight into microbial population structure and diversity of YBGs. Moreover, milk replacer may serve as a good applicant for improving gut microbial development in early-weaned YBGs. |
| تدمد: | 1475-2859 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c713467d0c353cafcbefebf864b9196Test https://doi.org/10.1186/s12934-021-01568-5Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6c713467d0c353cafcbefebf864b9196 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752859 |
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