Possibilities of colecalciferol therapy for tension type headache combined with hypovitaminosis D
| العنوان: | Possibilities of colecalciferol therapy for tension type headache combined with hypovitaminosis D |
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| المؤلفون: | A. A. Koloskova, O. V. Vorob’eva |
| المصدر: | Медицинский совет, Vol 0, Iss 21-1, Pp 46-54 (2022) |
| بيانات النشر: | Remedium, Ltd., 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | colecalciferol, chronic tension type headache, Medicine, pain, hipovitaminosis d, General Medicine, 25(он)d |
| الوصف: | Introduction. Modern studies indicate the therapeutic effect of vitamin D (VD) in chronic pain conditions, but there is no data on the use of VD in chronic tension type headache (CTTH) treatment.Objective: comparative evaluation of the effectiveness of various options for preventive treatment of CTTH: the use of colecalciferol, standard therapy of the disease and a combination of these methods.Materials and methods. 125 women with CTTH and hypovitaminosis D were treated in the study. The frequency, duration and intensity of headache (HF, HD and HI, respectively), HIT index, frequency of analgesics taking, pericranial muscle dysfunction were evaluated. The VD level was measured by the concentration of 25-hydroxyvitamin D [25(OH)D]. The patients received differentiated therapy for 16 weeks: group 1 – colecalciferol, group 2 – amitriptyline, group 3 – a combination of these medicines. Results. In group 1, HF, HD, HIT-index and the frequency of analgesics taking decreased, all p ≤ 0.001. In groups 2 and 3, the values of all CTTH-parameters decreased, all p Conclusions. Treatment of hypovitaminosis D in women with CTTH is accompanied by a decrease in HF, the effect of headache on the quality of life of patients and the frequency of taking analgesics. In CTTH and VD deficiency normalization of 25(OH)D level contributes to higher efficiency of standard therapy. |
| تدمد: | 2658-5790 2079-701X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0ba1afc5e3c4ab22f9b34ab7dfc76fTest https://doi.org/10.21518/2079-701x-2021-21-1-46-54Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8b0ba1afc5e3c4ab22f9b34ab7dfc76f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26585790 2079701X |
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