Laparoscopic hepatectomy for elderly patients
| العنوان: | Laparoscopic hepatectomy for elderly patients |
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| المؤلفون: | Chen, Ke, Pan, Yu, Maher, Hendi, Zhang, Bin, Zheng, Xue-yong |
| المصدر: | Medicine |
| بيانات النشر: | Wolters Kluwer Health, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Liver Neoplasms, Operative Time, laparoscopy, Blood Loss, Surgical, Length of Stay, elderly, meta-analysis, hepatectomy, Treatment Outcome, liver neoplasm, Humans, Blood Transfusion, Systematic Review and Meta-Analysis, Research Article, Aged |
| الوصف: | Background: As the general population continues to age, there is an increase need for surgical management of elderly patients. Compared to open hepatectomy (OH), laparoscopic hepatectomy (LH) offers earlier mobilization, less blood loss, and shorter postoperative hospital stay. However, whether these advantages of LH over OH are retained in elderly patients remains to be clarified. Therefore, in this study, we sought to evaluate the feasibility, safety, and potential benefits of LH for elderly patients. Methods: A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was performed to identify studies that compared LH and OH. Studies comparing LH in elderly and LH in nonelderly patients were also identified. Outcomes of interest included conversion rate, operative time, intraoperative estimated blood loss, length of hospital stay, rate and type of morbidity, mortality rate, margin status (R0), and long-term oncologic outcomes. Results: Nine studies met our inclusion criteria for this analysis. Of these, 5 compared LH and OH in elderly patients, 3 compared LH in elderly and nonelderly patients, and 1 included both outcomes. Compared to those with OH, elderly patients who underwent LH had similar operative times [weighted mean difference (WMD) = 1.15 minutes; 95% confidence interval (CI): −28.28–30.59, P = .94], less intraoperative blood loss (WMD = −0.71 mL; 95% CI: −1.29 to −0.16, P = .01), a lower rate of transfusion [risk ratio (RR) = 0.61, 95% CI: 0.40–0.94, P = .02], comparable R0 rates (RR = 1.01; 95% CI: 0.96–1.07, P = .70), less postoperative complications (RR = 0.61, 95% CI: 0.48–0.76, P |
| اللغة: | English |
| تدمد: | 1536-5964 0025-7974 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid________::a971cc180a52857e647b0d688b1cddbaTest http://europepmc.org/articles/PMC6078667Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid..........a971cc180a52857e647b0d688b1cddba |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15365964 00257974 |
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