دورية أكاديمية
Gastrectomy with or without Complete Omentectomy for Advanced Gastric Cancer: A Meta-Analysis
| العنوان: | Gastrectomy with or without Complete Omentectomy for Advanced Gastric Cancer: A Meta-Analysis |
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| المؤلفون: | Maurizio Zizzo, Magda Zanelli, Francesca Sanguedolce, Andrea Palicelli, Stefano Ascani, Andrea Morini, David Tumiati, Federica Mereu, Antonia Lavinia Zuliani, Melissa Nardecchia, Francesca Gatto, Manuel Zanni, Alessandro Giunta |
| المصدر: | Medicina, Vol 58, Iss 9, p 1241 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | omentum, omentectomy, gastric cancer, gastrectomy, outcomes, Medicine (General), R5-920 |
| الوصف: | Background and Objectives: Surgery remains the only possible curative treatment for advanced gastric cancer (AGC). Peritoneal metastases are estimated to occur in approximately 55–60% AGC patients. Greater omentum is the most common metastatic area in AGC. At present, omentectomy alone or bursectomy are usually carried out during gastric cancer surgery. We performed a meta-analysis in order to evaluate long-term and short-term outcomes among AGC patients, who have undergone radical gastrectomy with or without complete omentectomy (CO). Materials and Methods: We performed a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Meta-analysis was performed by use of RevMan (Computer program) Version 5.4. Results: The eight included studies covered an approximately 20 years long study period (2000–2018). Almost all included studies were retrospective ones and originated from Asian countries. Meta-analysis indicated gastrectomy without CO as significantly associated with longer 3-year (RR: 0.94, 95% CI: 0.90–0.98, p = 0.005) and 5-year overall survivals (OS) (RR: 0.93, 95% CI: 0.88–0.98, p = 0.007). Moreover, we found longer operative time (MD: 24.00, 95% CI: −0.45–48.45, p = 0.05) and higher estimated blood loss (MD: 194.76, 95% CI: 96.40–293.13, p = 0.0001) in CO group. Conclusions: Non-complete omentectomy (NCO) group had a statistically greater rate in 3-year and 5-year OSs than the CO group, while the CO group had significantly longer operative time and higher estimated blood loss than the NCO group. Further randomized, possibly multi-center trials may turn out of paramount importance in confirming our results. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1648-9144 1010-660X |
| العلاقة: | https://www.mdpi.com/1648-9144/58/9/1241Test; https://doaj.org/toc/1010-660XTest; https://doaj.org/toc/1648-9144Test |
| DOI: | 10.3390/medicina58091241 |
| الوصول الحر: | https://doaj.org/article/85e1363c1e2049a983cee0c956a82895Test |
| رقم الانضمام: | edsdoj.85e1363c1e2049a983cee0c956a82895 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16489144 1010660X |
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| DOI: | 10.3390/medicina58091241 |