دورية
Acupuncture Stimulation at Taixi Point: Effect on Technetium-99m Methylenediphosphonate Bioavailability in Rats
| العنوان: | Acupuncture Stimulation at Taixi Point: Effect on Technetium-99m Methylenediphosphonate Bioavailability in Rats |
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| المؤلفون: | de Souza, Deise Elisabete, de Souza, Raphael Sancho Sisley, Manoel, Cristiano Viana, Pereira, Marcia de Oliveira, do Carmo, Fernanda Santos, da Fonseca, Adenilson de Souza, Bernardo-Filho, Mario |
| المصدر: | Medical Acupuncture; June 2011, Vol. 23 Issue: 2 p93-99, 7p |
| مستخلص: | AbstractBackground:Various methods, including those used in nuclear medicine, have been used in attempts to obtain scientific evidence about TCM techniques, including acupuncture and moxibustion. Evaluating the bioavailability of radiopharmaceuticals in rats is one way to determine the effects of stimulating acupuncture points.Objective:The aim of this work was to investigate the effects of the stimulation of acupuncture point Taixi (KI 3) on the bioavailability of the radiopharmaceutical technetium-99m methylenediphosphonate (99mTc-MDP) in male Wistar rats.Subjects:Ten healthy male Wistar rats were used in this study.Intervention:Therats were allocated into two groups, a control group (CG) and a treated group (TG). The TG group of rats was bilaterally stimulated at acupuncture point KI 3 with stainless steel needles. Ocular plexus administration of 99mTc-MDP (7.4 MBq) was carried out 10 minutes after every needle insertionin the rats. After 180 minutes, the animals were rapidly sacrificed, the organs isolated, the radioactivity determined in a well γ counter, and the percentage per gram of tissue of injected dose (%ID/g) was determined.Results:According to anunpaired t-test, the %ID/g was significantly decreased (p< 0.05) in the Large Intestine of the rats in the TG (0.167 ± 0.056), compared to the Large Intestine in the CG (0.370 ± 0.142) and in Bones of the TG (0.562 ± 0.054), compared to the CG (0.873 ± 0.282).Conclusions:These results may suggest that acupuncture stimulation in the acupoint KI 3 might induce physiological responses capable of altering the bioavailability of the radiopharmaceutical 99mTc-MDP. However, further rigorous experimental studies to examine the effectiveness in either acupuncture points need to be carried out. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 19336586 19336594 |
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| DOI: | 10.1089/acu.2011.0791 |