Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation
| العنوان: | Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation |
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| المؤلفون: | Estruch, M, Sanchez-Quesada, JL, Llanos, JO, Benitez, S |
| المصدر: | MEDIATORS OF INFLAMMATION r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| بيانات النشر: | Hindawi Publishing Corporation, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | conformation, pathophys, lipid peroxide, alpha tocopherol, ligand, immune response, angiogenesis, endothelial progenitor cell, 1 alkyl 2 acetylglycerophosphocholine esterase, mononuclear cell, T lymphocyte, apolipoprotein B, animal, endothelium cell, phospholipase C, cell regeneration, pathophysiology, lipopolysaccharide, apoptosis, article, unclassified drug, enzyme activity, hydrolysis, priority journal, monocyte, cytotoxicity, lipids (amino acids, peptides, and proteins), monocyte chemotactic protein 1, antiinflammatory agent, leukocyte, glycosylation, Article Subject, antigen antibody complex, review, interleukin 8, chemistry, sphingomyelin phosphodiesterase, sphingomyelin, physical chemistry, human, fibroblast growth factor 2, umbilical vein endothelial cell, proteoglycan, electronegative low density lipoprotein, cell differentiation, inflammation, cytology, phospholipase A2, oxidized low density lipoprotein, pathology, fatty acid, atherosclerosis, low density lipoprotein, oxygen |
| الوصف: | Electronegative low density lipoprotein (LDL(-)) is a minor modified fraction of LDL found in blood. It comprises a heterogeneous population of LDL particles modified by various mechanisms sharing as a common feature increased electronegativity. Modification by oxidation is one of these mechanisms. LDL(-) has inflammatory properties similar to those of oxidized LDL (oxLDL), such as inflammatory cytokine release in leukocytes and endothelial cells. However, in contrast with oxLDL, LDL(-) also has some anti-inflammatory effects on cultured cells. The inflammatory and anti-inflammatory properties ascribed to LDL(-) suggest that it could have a dual biological effect. |
| وصف الملف: | text/xhtml |
| اللغة: | English |
| تدمد: | 0962-9351 |
| DOI: | 10.1155/2013/181324 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ae636aa62a4b75cd55c102127817287Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.dedup.wf.001..4ae636aa62a4b75cd55c102127817287 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09629351 |
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| DOI: | 10.1155/2013/181324 |