Isolation and Characterization of Fish-Gut Bacillus spp. as Source of Natural Antimicrobial Compounds to Fight Aquaculture Bacterial Diseases
| العنوان: | Isolation and Characterization of Fish-Gut Bacillus spp. as Source of Natural Antimicrobial Compounds to Fight Aquaculture Bacterial Diseases |
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| المؤلفون: | Paula Enes, Pedro Pousão-Ferreira, Maria José Saavedra, Aires Oliva-Teles, Russell Jerusik, Rafaela Santos, Cláudia R. Serra |
| المصدر: | Marine Biotechnology. 23:276-293 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, Vibrio anguillarum, medicine.drug_class, Antibiotics, Bacillus, Aquaculture, Biology, 01 natural sciences, Applied Microbiology and Biotechnology, law.invention, Microbiology, Fish Diseases, 03 medical and health sciences, Probiotic, law, 010608 biotechnology, medicine, Animals, business.industry, Probiotics, Biofilm, Quorum Sensing, Bacterial Infections, Antimicrobial, biology.organism_classification, Sea Bream, Anti-Bacterial Agents, Gastrointestinal Microbiome, Aeromonas hydrophila, 030104 developmental biology, Photobacterium damselae, Biofilms, Bass, business |
| الوصف: | Aquaculture is responsible for more than 50% of global seafood consumption. Bacterial diseases are a major constraint to this sector and associated with misuse of antibiotics, pose serious threats to public health. Fish-symbionts, co-inhabitants of fish pathogens, might be a promising source of natural antimicrobial compounds (NACs) alternative to antibiotics, limiting bacterial diseases occurrence in aquafarms. In particular, sporeforming Bacillus spp. are known for their probiotic potential and production of NACs antagonistic of bacterial pathogens and are abundant in aquaculture fish guts. Harnessing the fish-gut microbial community potential, 172 sporeforming strains producing NACs were isolated from economically important aquaculture fish species, namely European seabass, gilthead seabream, and white seabream. We demonstrated that they possess anti-growth, anti-biofilm, or anti-quorum-sensing activities, to control bacterial infections and 52% of these isolates effectively antagonized important fish pathogens, including Aeromonas hydrophila, A. salmonicida, A. bivalvium, A. veronii, Vibrio anguillarum, V. harveyi, V. parahaemolyticus, V. vulnificus, Photobacterium damselae, Tenacibaculum maritimum, Edwardsiela tarda, and Shigella sonnei. By in vitro quantification of sporeformers' capacity to suppress growth and biofilm formation of fish pathogens, and by assessing their potential to interfere with pathogens communication, we identified three promising candidates to become probiotics or source of bioactive molecules to be used in aquaculture against bacterial aquaculture diseases. |
| تدمد: | 1436-2236 1436-2228 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3ed7cc2013e2580291a5afb07021a9Test https://doi.org/10.1007/s10126-021-10022-xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....6a3ed7cc2013e2580291a5afb07021a9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14362236 14362228 |
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