التفاصيل البيبلوغرافية
| العنوان: |
Initial clinical evaluation of a non-contrast-enhanced MR angiography method in the distal lower extremities. |
| المؤلفون: |
Priest, Andrew Nicholas, Joubert, Ilse, Winterbottom, Andrew Philip, See, Teik Choon, Graves, Martin John, Lomas, David John |
| المصدر: |
Magnetic Resonance in Medicine; Dec2013, Vol. 70 Issue 6, p1644-1652, 9p |
| مستخلص: |
Purpose To report the initial experience and diagnostic performance applying a novel flow-dependent non-contrast-enhanced MR angiography ( NCE- MRA) method, in patients with suspected peripheral vascular disease, in comparison with established contrast-enhanced MRA ( CE- MRA). Methods The lower legs of 34 patients were imaged at 1.5 T with both NCE- MRA and CE- MRA. The NCE- MRA method consisted of a cardiac-gated balanced- SSFP sequence with controllable flow-suppression preparation. Flow-suppressed and unsuppressed datasets were subtracted to obtain angiograms. Two experienced radiologists assessed both NCE- MRA and CE- MRA images, first independently and then in consensus to resolve significant disagreements. Signal loss, vessel conspicuity, vascular disease, venous contamination, artifacts, and diagnostic confidence were assessed. Results Using the CE- MRA as the 'gold standard,' the per-segment sensitivity and specificity for detection of significant disease were 81.7% and 90.9%, respectively. Mean diagnostic confidence (scale 0-4) was 3.4 for NCE- MRA and 3.9 for CE- MRA. Most vessel segments were well visualized but the popliteal arteries often suffered some technique-related signal loss. Conclusions The NCE- MRA method was able to visualize most vessel segments with good or excellent confidence, few artifacts, and excellent background suppression, giving moderate agreement with CE- MRA. However, some segments were poorly visualized, probably due to flow profile distortion in these patients. Magn Reson Med 70:1644-1652, 2013. © 2013 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
