التفاصيل البيبلوغرافية
| العنوان: |
Increased Syk phosphorylation leads to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus. |
| المؤلفون: |
Iwata, S1, Yamaoka, K1, Niiro, H2, Jabbarzadeh-Tabrizi, S2, Wang, S-P1, Kondo, M1, Yoshikawa, M1, Akashi, K2, Tanaka, Y3 |
| المصدر: |
Lupus. Jun2015, Vol. 24 Issue 7, p695-704. 10p. |
| مصطلحات موضوعية: |
*PHOSPHORYLATION, *B cells, *SYSTEMIC lupus erythematosus, *GENETIC overexpression, *COMPLEMENT activation, *PATIENTS |
| مستخلص: |
The article focuses on the study which investigates the effects of increased syk phosphorylation to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus (SLE). It states that pronounced phosphorylation and expression of Syk were identified in B cells from SLE patients than healthy donors. It mentions that activatd Syk-mediated TRAF-6 pathway results to abberant activation of B cells in SLE. |
| قاعدة البيانات: |
Academic Search Index |
