Relations of liver fat with prevalent and incident chronic kidney disease in the Framingham Heart Study: A secondary analysis
| العنوان: | Relations of liver fat with prevalent and incident chronic kidney disease in the Framingham Heart Study: A secondary analysis |
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| المؤلفون: | Udo Hoffmann, Alison Pedley, Joseph M. Massaro, Emelia J. Benjamin, Michelle T. Long, Robert M. Wilechansky |
| المصدر: | Liver Int |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Renal function, urologic and male genital diseases, Article, Framingham Heart Study, Non-alcoholic Fatty Liver Disease, Internal medicine, Multidetector Computed Tomography, Epidemiology, Prevalence, medicine, Albuminuria, Humans, Longitudinal Studies, Renal Insufficiency, Chronic, Aged, Hepatology, business.industry, Incidence, Fatty liver, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, Massachusetts, Female, Microalbuminuria, Steatosis, business, Cohort study, Kidney disease |
| الوصف: | BACKGROUND & AIMS Prior studies demonstrated an association between non-alcoholic fatty liver disease and chronic kidney disease (CKD), though data are conflicting. We examined the association between liver fat and prevalent and incident CKD in the Framingham Heart Study (FHS). METHODS We included FHS participants who underwent computed tomography (CT) from 2002 to 2005 (n = 1315). After excluding heavy alcohol use (n = 211) and missing covariates (n = 117), the final sample included 987 participants. For the incident CKD analysis, we excluded 73 participants with prevalent CKD. Liver fat was measured by the average liver attenuation on CT. Estimated glomerular filtration rate (eGFR) was obtained using the CKD Epidemiology Collaboration Creatinine-Cystatin C equation, and CKD was defined as eGFR |
| تدمد: | 1478-3231 1478-3223 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ead09be150c1e360a30dd6688e006aTest https://doi.org/10.1111/liv.14125Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....59ead09be150c1e360a30dd6688e006a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14783231 14783223 |
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